| Cat. No. |
Product Name |
Information |
| PC-21077 |
GS-441524
Viral RdRp inhibitor
|
GS-441524 (GS441524) is the active metabolite of Remdesivir, inhibits viral RNA dependent RNA polymerase (RdRp) from the Flaviviridae family. |
| PC-21075 |
GS-5245
Antiviral
|
GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo. |
| PC-21016 |
SARS-CoV-2 3CLpro inhibitor C5a
SARS-CoV-2 3CLpro inhibitor
|
SARS-CoV-2 3CLpro inhibitor C5a is a potent, non-covalent, non-peptide inhibitor of 3C-like protease (3CLpro) inhibitor with dissociation constant (Kd) of 170 nM, IC50 of 0.7 uM against recombinant SARS-CoV-2 3CLpro. |
| PC-49865 |
TKB248
SARS-CoV-2 Mpro inhibitor
|
TKB248 (TKB-248) is a potent, specific SARS-CoV-2 Mpro inhibitor with IC50 of 74 nM, exhibits highly potent anti-SARS-CoV-2 activity with EC50 and EC95 values of 0.22 and 0.87 µM, respectively. |
| PC-49864 |
TKB245
SARS-CoV-2 Mpro inhibitor
|
TKB245 (TKB-245) is a potent, specific SARS-CoV-2 Mpro inhibitor with IC50 of 7 nM, exhibits highly potent anti-SARS-CoV-2 activity with EC50 and EC95 values of 0.03 and 0.53 µM, respectively. |
| PC-49668 |
WNN2048-F004
SARS-CoV-2 Mpro inhibitor
|
WNN2048-F004 (Compound 4a) is a potent, covalent, nonpeptidomimetic SARS-CoV-2 main protease (Mpro) inhibitor with biochemical IC50 of 103 nM, covalently binds to the substrate-binding pocket (Cys145) of SARS-CoV-2 Mpro. |
| PC-49579 |
Mpro inhibitor GD-9
SARS-CoV-2 Mpro inhibitor
|
Mpro inhibitor GD-9 is a potent, covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.18 uM, exhibits antiviral potency against SARS-CoV-2 with EC50 of 2.64 uM. |
| PC-49528 |
DMGA
SARS-CoV-2 PLpro inhibitor
|
DMGA is an allosteric and covalent inhibitor of SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro) with IC50 of 9.4 uM, covalently binds with C270 of the SARS-CoV-2 PLpro. |
| PC-49424 |
Difluorobenztropine
SARS-CoV-2 entry inhibitor
|
Difluorobenztropine (AHN 1-055) is a direct-acting SARS-CoV-2 entry inhibitor that targets the SARS-CoV-2 spike fusion peptide domain. |
| PC-49423 |
TMPRSS2 inhibitor BC-11
TMPRSS2 inhibitor
|
TMPRSS2 inhibitor BC-11 is a specific, covalent transmembrane protease serine 2 (TMPRSS2) inhibitor with IC50 of 1.44 uM in vitro TMPRSS2 enzymatic assay. |
| PC-49342 |
GC-14
SARS-CoV-2 Mpro inhibitor
|
GC-14 is a potent, selective and non-covalent non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.4 uM, displays excellent selectivity over cathepsins B, F, K, L, and caspase 3 (IC50>50 uM). |
| PC-49335 |
WU-04
SARS-CoV-2 3CLpro inhibitor
|
WU-04 (WPV01) is a highly potent, non-covalent, orally active inhibitor of SARS-CoV-2 3C-like protease (3CLpro) with IC50 of 72 nM, binding Kd of 37 nM. |
