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Cat. No. Product Name Information
PC-38459

GS-621763

SARS-CoV-2 Inhibitor

GS-621763 is an oral prodrug of remdesivir parent nucleoside GS-441524, inhibits SARS-CoV-2, including variants of concern in cell culture (EC50=0.11 to 0.73 uM) and human airway epithelium organoids.
PC-73461

Molnupiravir

SARS-CoV-2 inhibitor

EIDD-2801 (MK-4482, Molnupiravir) is a highly potent ribonucleoside analog, and prodrug of EIDD-1931, exhibits broad-spectrum antiviral inhibitor of multiple RNA viruses including SARS-CoV-2.
PC-73341

Coronastat

SARS-CoV-2 3CLpro inhibitor

Coranastat (NK01-63) is a GC376 analog with improved potency, and highly potent, selective SARS-CoV-2 3CL protease inhibitor with IC50 of 16 nM, exhibits antiviral potency with EC50 of 6 nM in Huh-7ACE2 cellular assays.
PC-73340

MAC-5576

SARS-CoV-2 3CLpro inhibitor

MAC-5576 (MAC5576) is a small molecule, covalent inhibitor of coronavirus SARS-CoV 3CLpro with IC50 of 0.5 uM, inhibits SARS-CoV-2 3CL protease with IC50 of 0.093 uM.
PC-73233

SSAA09E2

Spike-ACE2 inhibitor

SSAA09E2 is a small molecule inhibitor of SARS entry, blcks early interactions of SARS-CoV surface glycoprotein S (SARS-S) with angiotensin converting enzyme 2 (ACE2), also inhibits SARS-CoV-2 Spike-ACE2 interaction.
PC-73013

Z222979552

SARS-CoV-2 Mpro inhibitor

Z222979552 is a small molecule non-covalent SARS-CoV-2 Mpro inhibitor with IC50 of 1.0 uM.
PC-72893

(S)-chlorcyclizine

SARS CoV fusion inhibitor

(S)-chlorcyclizine ((S)-CCZ) is an approved antihistamine drug that is related to dichlorcyclizine (DCCZ), inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 6.91 and 4.09 uM.
PC-72889

NBCoV2

CoV fusion inhibitor

NBCoV2 is a highly potent small molecule viral fusion inhibitor with potential pan-Coronavirus activity (SARS-CoV IC50=13.8 nM, SARS-CoV-2 IC50=22.8 nM, MERS-CoV IC50=77 nM, cell-based single-cycle assays).
PC-72888

NBCoV1

Viral fusion inhibitor

NBCoV1 is a highly potent small molecule viral fusion inhibitor with potential pan-Coronavirus activity (SARS-CoV IC50=17 nM, SARS-CoV-2 IC50=51 nM, MERS-CoV IC50=75 nM, cell-based single-cycle assays).
PC-72808

CSNK2A inhibitor 2

CSNK2 inhibitor

CSNK2A inhibitor 2 (CK2 inhibitor Compound 2) is a potent, selective, cell active ATP-competitive inhibitor of host protein kinase Casein Kinase 2 (CSNK2A1/2, pIC50=8.5-8.6), inhibits the pathogenic β-coronaviruses including SARS-CoV-2 (MHV pIC50=8.6)
PC-72806

DS0464

SARS-CoV-2 nsp14 inhibitor

DS0464 is a selective, bisubstrate competitive inhibitor SARS-CoV-2 nonstructural protein 14 (nsp14) with IC50 of 1.1 uM, also selective against 28 out of 33 RNA, DNA, and protein MTases.
PC-72805

N-0385

TMPRSS2 inhibitor

N-0385 (N 0385, Ms-Gln-Phe-Arg-kbt) is a potent, selective inhibitor of TMPRSS2 with IC50 of 1.9 nM

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