| Cat. No. |
Product Name |
Information |
| PC-35231 |
GC376
3CLpro inhibitor
|
GC376 (GC-376) is a broad-spectrum antiviral agent that inhibits 3C or 3C-like proteases (3Cpro or 3CLpro) of picornaviruses, noroviruses, and coronaviruses with IC50 of 0.96 (MD145), 0.82 (TGEV) and 0.2 uM (HRV) in FRET protease assays. |
| PC-24517 |
N-0920
TMPRSS2 inhibitor
|
N-0920 (Cbz-QFR-kt) is highly potent, specific TMPRSS2 inhibitor with IC50 of 350 pM, displays high antiviral potency with IC50 of 0.3 nM and 0.09 nM for SARS-CoV-2 Variants EG.5.1 and JN.1 respectively. |
| PC-24476 |
AVI-4516
SARS-CoV-2 Mpro inhibitor
|
AVI-4516 is a potent, selective, covalent SARS-CoV-2 main protease (MPro) inhibitor with IC50 of 29 nM, demonstrates potent in vivo antiviral efficacy. |
| PC-24475 |
AVI-4773
SARS-CoV-2 Mpro inhibitor
|
AVI-4773 is a potent, selective, covalent SARS-CoV-2 main protease (MPro) inhibitor with IC50 of 38 nM, demonstrates potent in vivo antiviral efficacy. |
| PC-24429 |
WEHI-P4
SARS-CoV-2 PLpro inhibitor
|
WEHI-P4 is a highly potent, specific SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 19 nM and KD of 18 nM, cellular EC50 of 330 nM in in-cell FRET-based biosensor assays. |
| PC-24428 |
WEHI-P8
SARS-CoV-2 PLpro inhibitor
|
WEHI-P8 is a highly potent, specific, orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 12 nM and KD of 9 nM, cellular EC50 of 298 nM in in-cell FRET-based biosensor assays. |
| PC-24314 |
JNJ-9676
SARS-CoV-2 M protein inhibitor
|
JNJ-9676 is a potent, specific small-molecule inhibitor of SARS-CoV-2 and SARS-CoV, binds to SARS-CoV-2 M protein, reduces SARS-CoV-2 (B1 variant) production of viral RNA with EC50/EC90 of 94/132 nM respectively. |
| PC-24313 |
CIM-834
SARS-CoV-2 M protein inhibitor
|
CIM-834 is a potent, first-in-class, orally efficacious small molecule coronavirus assembly inhibitor, blocks the assembly of SARS-CoV-2, targets the viral membrane (M) protein, inhibits replication of a panel of SARS-CoV-2 isolates with mean EC50 of 112 nM and 84 nM in VeroE6–GFP and A549ACE2+TMPRSS2 cells, respectively. |
| PC-24181 |
Secutrelvir
SARS-CoV-2 3CLPro inhibitor
|
Secutrelvir is a potent, selective inhibitor of SARS-CoV 3CL protease (3CLpro) inhibitor. |
| PC-24173 |
Ratutrelvir
SARS-CoV-2 Mpro inhibitor
|
Ratutrelvir (Travatrelvir, 83-0060, TRX01) is a potent, selective inhibitor of SARS-CoV-2 main protease Mpro (3CL protease). |
| PC-23977 |
EPB-113
Coronavirus inhibitor
|
EPB-113 is a potent replication inhibitor of HCoV-229E with EC50 of 0.48 uM, also suppresses SARS-CoV-2, binds to hexameric nsp15 protein. |
| PC-23891 |
TKB272
SARS-CoV-2 Mpro inhibitor
|
TKB272 is a potent, selective inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 0.7 nM, effectively blocks the infectivity and replication of SARS-CoV-2 strains (SARS-CoV-2 WK-521, EC50=7.0 nM, VeroE6 cell). |
