| Cat. No. |
Product Name |
Information |
| PC-72663 |
DWP16001
SGLT-2 inhibitor
|
DWP16001 (Enavogliflozin, GCC 5694A) is a potent and selective sodium glucose co-transporter 2 (SGLT-2) inhibitor with IC50 of 0.46 nM (hSGLT2), > 700-fold selectivity against SGLT1. |
| PC-63375 |
KGA-2727
|
KGA-2727 is a potent, selective SGLT1 inhibitor with Ki of 97.4 nM, >100-fold selectivity over SGLT2. |
| PC-61451 |
Mizagliflozin
SGLT1 inhibitor
|
Mizagliflozin (DSP-3235, KGA-3235, GSK-1614235) is a potent, selective, orally active SGLT1 inhibitor with Ki of 27 nM, displays >350-fold selectivity over SGLT2. |
| PC-61383 |
Luseogliflozin
SGLT2 inhibitor
|
A potent, selective, orally acitve SGLT2 inhibitor with IC50 of 2.26 nM, 1650-fold selectivity over SGLT1. |
| PC-42592 |
Dapagliflozin
SGLT2 inhibitor
|
Dapagliflozin (BMS-512148) is a potent, selective, orally active hSGLT2 inhibitor with EC50 of 1.12 nM. |
| PC-42594 |
Canagliflozin
SGLT2 inhibitor
|
Canagliflozin (JNJ 28431754) is a highly potent and selective SGLT2 inhibitor with IC50 of 4.4, 3.7 and 2.0 nM for hSGLT2, rSGLT2 and mSGLT2, respectively. |
| PC-20194 |
Sergliflozin etabonate
SGLT2 inhibitor
|
Sergliflozin etabonate (GW869682X) is a potent, selective SGLT2 inhibitor with IC50 of 7.5 nM (hSGLT2), >200-fold selectivity over hSGLT1. |
| PC-49671 |
SGL5213
SGLT1 inhibitor
|
SGL5213 (SGL 5213) is potent, intestinal sodium-dependent glucose cotransporter (SGLT) inhibitor with IC50 of 29 and 20 nM for hSGLT1 and hSDGLT2, respectively. |
| PC-35748 |
TP0438836
|
TP0438836 is a potent, low-absorbable sodium-dependent glucose cotransporter (SGLT) inhibitor with IC50 of 28 nM/7 nM for hSGLT1 and hSGLT2, respectively. |
| PC-44120 |
Tofogliflozin
|
Tofogliflozin (CSG-452) is a potent, highly selective SGLT2 inhibitor with Ki of 2.9, 14.9, and 6.4 nM against human, rat, and mouse SGLT2, respectively. |
| PC-43518 |
Tofogliflozin hydrate
|
Tofogliflozin (CSG-452) is a potent, highly selective SGLT2 inhibitor with Ki of 2.9, 14.9, and 6.4 nM against human, rat, and mouse SGLT2, respectively. |
| PC-63416 |
JNJ-39933673 hemihydrate
|
JNJ-39933673 hemihydrate is a potent, selective SGLT2 inhibitor.. |
