| Cat. No. |
Product Name |
Information |
| PC-45085 |
T338C Src-IN-2
Src T338C inhibitor
|
T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM, also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM. |
| PC-45449 |
AMG-47a
Lck inhibitor
|
AMG-47a is a potent Lck kinase inhibitor with IC50 of 0.2 nM, selectively reduces the levels of EGFP-KRASG12V protein but do not affect EGFP protein in cells. |
| PC-42786 |
A-770041
Lck inhibitor
|
A-770041 (A770041) is a potent and selective small-molecule inhibitor of Lck kinase with IC50 of 147 nM. |
| PC-45439 |
KX1-004
Src inhibitor
|
KX1-004 is a non-ATP competitive Src-PTK inhibitor with IC50 of 40 uM. |
| PC-42539 |
KX2-391 mesylate
Src/pretubulin inhibitor
|
Tirbanibulin mesylate (KX2-391 mesylate) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-42538 |
KX2-391 dihydrochloride
Src inhibitor
|
Tirbanibulin (KX2-391 dihydrochloride) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-42537 |
Tirbanibulin
Src inhibitor
|
Tirbanibulin (KX2-391, KX 01) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-26293 |
1-NM-PP1
Src inhibitor
|
1-NM-PP1 is a cell-permeable PP1 analog and potent Src family kinases inhibitor with IC50 of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively, also inhibits PKD with IC50 of 398 nM (PKD2) and analog-sensitive CRK9 (CRK9AS). |
| PC-25884 |
CSK inhibitor 13
CSK inhibitor
|
CSK inhibitor 13 (SI-3, CSK-IN-1) is a potent, selective inhibitor of C-terminal Src kinase (CSK) with IC50 of <3 nM in HTRF assays, increases ZAP-70 phosphorylation in Jurkat cells with EC50 of 260 nM, does not inhibit LCK. |
| PC-25816 |
DCDBS84 hydrobromide
Integrin β3-Src SH3 inhibitor
|
DCDBS84 hydrobromide is a small molecule specifically targeting c‐Src SH3 RT‐loop with SPR Kd of 0.83 uM, disrupts the interaction of integrin β3 with Src SH3, selectively blocks αIIbβ3 outside‐in signaling and shows potent antithrombotic effect. |
| PC-25344 |
Reynoutrin
Fyn inhibitor
|
Reynoutrin (Quercetin-3-D-xyloside) is a flavonoid from Psidium cattleianum, with antioxidant and radical-scavenging activity, a potent inhibitor of Fyn, inhibits both the expression and phosphorylation of Fyn. |
| PC-24574 |
Src inhibitor PP1
Src inhibitor
|
PP1 is a potent, selective Src family tyrosine kinases inhibitor with IC50 of 5 and 6 nM for Lck and Fyn, respectively. |
