| Cat. No. |
Product Name |
Information |
| PC-21066 |
ZAP-70 inhibitor 20
ZAP-70 inhibitor
|
ZAP-70 inhibitor 20 is a potent, selective ZAP-70 kinase inhibitor with IC50 of 8 nM, shows high selectivity over PKC, p56 Lck, EGFR and Csk. |
| PC-21065 |
ZAP-70 inhibitor 26
ZAP-70 inhibitor
|
ZAP-70 inhibitor 26 is a potent, highly selective ZAP-70 kinase inhibitor with IC50 of 88 nM, shows high selectivity over structurally related Syk (IC50>10 uM). |
| PC-20602 |
BI 1342561
Syk inhibitor
|
BI 1342561 is a novel potent and selective SYK inhibitor developed to treat severe asthma. |
| PC-20601 |
BI 894416
Syk inhibitor
|
BI 894416 is a novel potent and selective SYK inhibitor developed to treat severe asthma. |
| PC-20054 |
MRL-SYKi
Syk inhibitor
|
MRL-SYKi is a potent, selective inhibitor of Syk (Spleen tyrosine kinase) with IC50 of <100 nM, also potently inhibits ZAP70 (24 nM in vitro). |
| PC-49627 |
MTX-216
Syk inhibitor
|
MTX-216 (MTX216) is a dual PI3K/EGFR inhibitor that blocks neurofibromin 1 loss of function (NF1LoF) melanoma cell growth in vitro and in vivo, suppresses the activity of SYK kinase with IC50 of 281 nM. |
| PC-49383 |
WC36
Syk-cSH2 inhibitor
|
WC36 is a potent, specific inhibitor of Syk-cSH2 with IC50 of 40 nM, inhibits Syk-cSH2-PIP3 binding, specifically and potently suppresses oncogenic activities of Syk in AML cells. |
| PC-45992 |
MNS
|
A potent, selective Src and Syk kinase inhibitor with IC50 of 29.3 uM and 2.5 uM, respectively. |
