| Cat. No. |
Product Name |
Information |
| PC-70328 |
HXJ 42
ZAP-70 inhibitor
|
HXJ 42 is a PP1 analog that has greater selectivity and potency for Zap-70(AS) over wild-type Zap-70, as assessed by Erk and Lat phosphorylation, as well as by proliferative responses of mature CD4+ cells. |
| PC-60451 |
TAK-659 hydrochloride
SYK inhibitor
|
TAK-659 hydrochloride (Mivavotinib, TAK659) is a potent, selective and orally available SYK inhibitor with IC50 of 3.2 nM. |
| PC-60450 |
TAK-659
SYK inhibitor
|
TAK-659 (TAK659, Mivavotinib) is a potent, selective and orally available SYK inhibitor with IC50 of 3.2 nM. |
| PC-45970 |
BAY 61-3606
Syk inhibitor
|
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
| PC-44143 |
BAY 61-3606 dihydrochloride
Syk inhibitor
|
BAY 61-3606 dihydrochloride is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
| PC-43303 |
PRT-060318
SYK inhibitor
|
PRT-060318 is a potent and selective Syk inhibitor with IC50 of 4 nM. |
| PC-45082 |
RO9021
Syk inhibitor
|
RO9021 is an orally bioavailable, ATP-competitive, highly selective inhibitor of Syk kinase with IC50 of 5.6 nM. |
| PC-22156 |
NMS-0963
Syk inhibitor
|
NMS-0963 (NMS0963) is a potent, selective spleen tyrosine kinase (SYK) inhibitor with biochemical IC50 of 3 nM, inhibits SYK kinase activity in SYK-dependent BaF3-TEL/SYK cells with IC50 of 27 nM. |
| PC-22084 |
Cevidoplenib dimesylate
Syk inhibitor
|
Cevidoplenib dimesylate (SKI-O-703) is a potent, selective, orally active spleen tyrosine kinase (Syk) inhibitor with IC50 of 6.2 nM. |
| PC-22082 |
PRT062607 hydrochloride
Syk inhibitor, PINK1 inhibitor
|
PRT062607 (P505-15) hydrochloride is a potent, highly specific, orally bioavailable inhibitor of Syk kinase with IC50 of 1 nM, also potently inhibits both insect and human PINK with an IC50 in the 0.5-3 µM range in HeLa cells and dopaminergic neurons. |
| PC-22081 |
PRT062607
Syk inhibitor, PINK1 inhibitor
|
PRT062607 (P505-15) is a potent, highly specific, orally bioavailable inhibitor of Syk kinase with IC50 of 1 nM, also potently inhibits both insect and human PINK with an IC50 in the 0.5-3 µM range in HeLa cells and dopaminergic neurons. |
| PC-21308 |
OXSI-2
Syk inhibitor
|
OXSI-2 is a putative and selective inhibitor of Syk with IC50 of 14 nM, inhibits convulxin-induced platelet functional responses. |
