| Cat. No. |
Product Name |
Information |
| PC-62118 |
VU 6008667
|
VU 6008667 is a potent, highly selective M5 negative allosteric modulator with IC50 of 1.2 uM. |
| PC-61894 |
PF-3635659
|
PF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM, shows potential for the treatment of chronic obstructive pulmonary disease (COPD).. |
| PC-61893 |
Fesoterodine fumarate
|
Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. |
| PC-61892 |
Fesoterodine maleate
|
Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. |
| PC-61891 |
Fesoterodine
|
Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. |
| PC-61789 |
PPBI
|
PPBI is a novel potent, selective, full M1 muscarinic agonist with EC50 of 5, 8, and 21 nM for human, rat, and mouse M1 receptors, respectively. |
| PC-61761 |
Glycopyrronium bromide
|
Glycopyrronium bromide (CHF 5259) is a peripherally-acting quaternary ammonium antimuscarinic agent with little or no central nervous system activity. |
| PC-61049 |
THRX-200495
|
A novel, dual-acting muscarinic receptor antagonist and β2-adrenoceptor agonist (MABA) with pKi of 9.21/9.53 for hM2/M3, pKi of 9.37 for β2-adrenoceptor. |
| PC-61048 |
V0162
|
A novel, high affinity and long-acting antagonist of human M3 muscarinic acetylcholine receptor with pKi of 9.03-9.21. |
| PC-61047 |
AZD 9164
|
A novel highly potent, selective, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, 10-fold selectivity over M2 (pIC50=9.0). |
| PC-61046 |
AZD 8683
|
A highly potent, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, inhibits M3 receptor in guinea pig trachea with pA2 of 9.4. |
| PC-60328 |
LY2033298
|
A potent, selective, positive allosteric modulator of muscarinic M4 receptors. |
