ADC Cytotoxin compound (inhibitors, antagonists, natural products)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-26475	FL118 ADC payload, DDX5 inhibitor	FL118 is a camptothecin derivative and payload for antibody-drug conjugates (ADCs) through topoisomerase I inhibition and proteasome-mediated degradation of anti-apoptotic proteins, also is a potent DDX5 (p68) degrader.
PC-46001	MMAF-OMe	An antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. It is linked to an antibody with high affinity to structures on cancer cells, causing MMAF to accumulate in such cells.
PC-45998	MMAD hydrochloride	A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs)..
PC-45742	Ansamitocin P-3	A microtubule depolymerizing agent that can be isolated from culture broths of certain Gram-positive bacteria.
PC-45045	PNU-159682	A highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity.

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