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Request The Product List ofAMPK AMPK

Cat. No. Product Name Information
PC-20473

RX-375

AMPK activator

RX-375 (RX375) is an indirect small-molecule activator of AMPK by directly binds to Prohibitins (PHB1 and PHB2), induces dissociation of AMPK-PHBs complex.
PC-47024

PXL770

AMPK activator

PXL770 is a novel orally bioavailable, small-molecule direct AMPK activator with EC50 of 16.2, 42.1 and 64 nM for α1β1γ1, α1β1γ2 and α1β1γ3, directly increases AMPK activity by both allosteric activation and protection from dephosphorylation.
PC-47019

RSVA405

AMPK activator

RSVA405 is a small-molecule activator of AMPK, facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR and promotes autophagy to increase Aβ degradation by the lysosomal system with EC50 of 1 uM.
PC-38664

MSG011

pan AMPK activator

MSG011 is a potent, pan AMPK isoform activator with EC50 of 140.4 nM, 248.9 nM, 553.4 nM, and 472.9 nM for α1β1γ1, α1β2γ1, α2β1γ1, and α2β2γ1, respectively.
PC-73284

HTH-02-006

NUAK2 inhibitor

HTH-02-006 is a potent, selective reversible inhibitor of NUAK1/2 with binding IC50 of 8/126 nM, respectively.
PC-35642

BL-AD008

AMPK activator

BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK.
PC-35496

AMPK activator 991

AMPK activator

AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro, binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively.
PC-35495

AMPK activator SC4

AMPK activator

AMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3, the predominant AMPK isoform complexes in human skeletal muscle.
PC-35414

GSK621

AMPK activator

GSK621 (GSK-621) is a potent, specific AMPK agonist (activator), induces cytotoxicity in AML (IC50=13-30 uM) but not in normal hematopoietic cells.
PC-35331

BAY-3827

AMPK inhibitor

BAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK with IC50 of 0.4 nM (10 µM ATP) and 15 nM (2 mM ATP), respectively.
PC-43522

Dorsomorphin

AMPK inhibitor

Dorsomorphin (BML-275, Compound C) is a potent, selective and reversible AMPK inhibitor with Ki of 109 nM, shows no no significant activity on ZAPK, SYK, PKCθ, PKA and JAK3.
PC-43521

Dorsomorphin dihydrochloride

AMPK inhibitor

Dorsomorphin (BML-275, Compound C) is a potent, selective and reversible AMPK inhibitor with Ki of 109 nM, shows no no significant activity on ZAPK, SYK, PKCθ, PKA and JAK3.

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