| Cat. No. |
Product Name |
Information |
| PC-42495 |
PD 123319 ditrifluoroacetate
AT2 receptor antagonist
|
PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM. |
| PC-42494 |
PD 123319
AT2 receptor antagonist
|
PD 123319 (PD123,319) potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM. |
| PC-27613 |
L-162313
AT1R/AT2R agonist
|
L-162313 (L-162,313) is a potent, selective non-peptide agonist of angiotensin II AT1 and AT2 receptors with IC50 of 1.1 and 2.0 nM, stimulates phosphoinositide hydrolysis in COS-7 cells transfected with the rat AT1 receptor with EC50 of 33 nM. |
| PC-27462 |
Foberigan
AT2R antagonist
|
Foberigan is a potent, selective Angiotensin II type 2 receptor (AT2R) antagonist. |
| PC-27459 |
TRV023
AT1R agonist
|
TRV023 (TRV120023) is a selective, β-arrestin-biased agonist of angiotensin II type 1 receptor (AT1R) with pEC50 of 7.66 and 7.62 for β-Arrestin 1 and β-Arrestin 2 respectively. |
| PC-27458 |
TRV120056
AT1R agonist
|
TRV120056 (TRV056) is a selective G protein-biased agonist to activate canonical Gq/11 signaling of the angiotensin II type 1 receptor (AT1R). |
| PC-27457 |
TRV055
AT1R agonist
|
TRV055 (TRV120055) is a selective Gq/11 biased agonist to activate canonical Gq/11 signaling of the angiotensin II type 1 receptor (AT1R). |
| PC-25932 |
Buloxibutid
AT2R agonist
|
Buloxibutid (C21) is an orally available, selective, high-affinity angiotensin II type 2 receptor (AT2R) agonist with Ki of 0.4 nM, >10,000-fold selective over AT1R. |
| PC-23855 |
Irbesartan
AT1 receptor antagonist
|
Irbesartan (SR 47436) is a potent, selective nonpeptide AT1 angiotensin II receptor (AT1 receptor) antagonist, inhibits [125I]AII binding to AT1 subtype receptors in rat liver membrane with IC50 of 1.7 nM, with no effect on AT2 subtypes. |
| PC-22028 |
BIO101
MasR agonist
|
BIO101 (20-hydroxyecdysone, Crustecdysone) is a small molecule agonist of Mas receptor (MasR), has anti-inflammatory, anti-fibrotic and cardioprotective properties, shows potential treatment for respiratory failure in COVID-19. |
| PC-21224 |
A779
Angiotensin-(1-7) inhibitor
|
A779 is a potent, selective antagonist of angiotensin-(1-7) receptor Mas, blocks the antidiuretic effect of Ang-(1-7) in vivo. |
| PC-45431 |
Valsartan
|
An angiotensin II receptor antagonist for treatment of high blood pressure and heart failure.. |
