| Cat. No. |
Product Name |
Information |
| PC-45692 |
BIBS-39
Angiotensin receptor antagonist
|
BIBS-39 (BIBS 39) is a selective nonpeptide angiotensin II receptor antagonist with Ki of 29 nM and 480 nM for AT1 and AT2 respectively. |
| PC-44124 |
Azilsartan
AT1 inhibitor
|
Azilsartan (TAK-536) is a specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension. |
| PC-45317 |
Losartan potassium
AT1 inhibitor, PAX8 inhibitor
|
Losartan potassium (DuP-753) is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension), also inhibits PAX8 expression and function. |
| PC-45316 |
Losartan
AT1 inhibitor, PAX8 inhibitor
|
Losartan (DuP-753) is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension), also inhibits PAX8 expression and function. |
| PC-42495 |
PD 123319 ditrifluoroacetate
AT2 receptor antagonist
|
PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM. |
| PC-42494 |
PD 123319
AT2 receptor antagonist
|
PD 123319 (PD123,319) potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM. |
| PC-27462 |
Foberigan
AT2R antagonist
|
Foberigan is a potent, selective Angiotensin II type 2 receptor (AT2R) antagonist. |
| PC-27459 |
TRV023
AT1R agonist
|
TRV023 (TRV120023) is a selective, β-arrestin-biased agonist of angiotensin II type 1 receptor (AT1R) with pEC50 of 7.66 and 7.62 for β-Arrestin 1 and β-Arrestin 2 respectively. |
| PC-27458 |
TRV120056
AT1R agonist
|
TRV120056 (TRV056) is a selective G protein-biased agonist to activate canonical Gq/11 signaling of the angiotensin II type 1 receptor (AT1R). |
| PC-27457 |
TRV055
AT1R agonist
|
TRV055 (TRV120055) is a selective Gq/11 biased agonist to activate canonical Gq/11 signaling of the angiotensin II type 1 receptor (AT1R). |
| PC-25932 |
Buloxibutid
AT2R agonist
|
Buloxibutid (C21) is an orally available, selective, high-affinity angiotensin II type 2 receptor (AT2R) agonist with Ki of 0.4 nM, >10,000-fold selective over AT1R. |
| PC-24210 |
Telmisartan
AT1 receptor antagonist
|
Telmisartan (BIBR-277) is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), inhibits binding of 125I-AngII to AT1 receptor with IC50 of 9.2 nM. |
