| Cat. No. |
Product Name |
Information |
| PC-45427 |
Prexasertib
CHK1 inhibitor
|
Prexasertib (LY2606368, ACR-368) is a potent, selective, ATP-competitive inhibitor of CHK1 with Ki of 0.9 nM. |
| PC-44037 |
LY2603618
CHK1 inhibitor
|
Rabusertib (LY2603618) is a potent and selective small molecule inhibitor of Chk1 (IC50= 7 nM). |
| PC-42769 |
AZD-7762
Chk1/Chk2 inhibitor
|
AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM. |
| PC-44033 |
CCT241533 hydrochloride
Chk2 inhibitor
|
CCT241533 hydrochloride is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM. |
| PC-44032 |
CCT241533
Chk2 inhibitor
|
CCT241533 is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM. |
| PC-45429 |
CCT244747
CHK1 inhibitor
|
CCT244747 (CCT 244747) is a potent, highly selective, orally active, ATP competitive CHK1 inhibitor with biochemical IC50 of 8 nM. |
| PC-45574 |
CCT245737
CHK1 inhibitor
|
CCT245737 (SRA-737) is a highly potent, selective, ATP-competitive inhibitor of Chk1 with IC50 of 1.3 nM. |
| PC-24519 |
LY2880070
CHK1 inhibitor
|
LY2880070 (LY-2880070) is a highly potent, selective and orally active CHK1 inhibitor with IC50 of 0.5 nM. |
| PC-24518 |
BEN-28010
CHK1 inhibitor
|
BEN-28010 is a potent selective, orally bioavailable and brain-penetrant checkpoint kinase 1 (CHK1) inhibitor with IC50 of 4 nM, 450-fold selective over CHK2. |
| PC-21172 |
2OH-BNPP1
BUB1 inhibitor
|
2OH-BNPP1 is a small molecule inhibitor of BUB1 (budding uninhibited by benzimidazoles-1) kinase, abrogates TGFβ signaling. |
