| Cat. No. |
Product Name |
Information |
| PC-45763 |
(Z)-Mirin
MRE11 inhibitor
|
(Z)-Mirin is a small molecule inhibitor of MRN (Mre11-Rad50-Nbs1) pathway that inhibits Mre11-associated exonuclease activity. |
| PC-42079 |
HUHS-015
PCA-1/ALKBH3 inhibitor
|
HUHS-015 (HUHS015) is a potent, orally active prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with IC50 of 0.67 uM. |
| PC-43227 |
TH-588 hydrochloride
MTH1 inhibitor
|
TH-588 hydrochloride is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 5 nM. |
| PC-43226 |
TH-588
MTH1 inhibitor
|
TH-588 is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 5 nM. |
| PC-45105 |
TH-287 hydrochloride
MTH1 inhibitor
|
TH-287 hydrochloride is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 0.8 nM. |
| PC-45104 |
TH-287
MTH1 inhibitor
|
TH-287 is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 0.8 nM. |
| PC-26990 |
DHX33 inhibitor BCD38
DHX33 inhibitor
|
BCD38 is a small molecule inhibitor of RNA helicase DHX33, suppresses the helicase activity of DHX33 in vitro, induces similar effects as DHX33 knockdown. |
| PC-26961 |
NSC37215
TREX1 inhibitor
|
NSC37215 is an effective small molecule inhibitor of three prime repair exonuclease 1 (TREX1) with IC50 of 4.72 uM and 30.32 uM for human and mouse TREX1 respectively. |
| PC-26960 |
TREX1-IN-4
TREX1 inhibitor
|
TREX1-IN-4 (Compound 96) is a potent dual inhibitor of DNA nucleases TREX1 and TREX2 with IC50 of <0.1 μM and < 1 μM. |
| PC-26959 |
TREX1-IN-3
TREX1 inhibitor
|
TREX1-IN-3 (Compound 95) is a potent dual inhibitor of DNA nucleases TREX1 and TREX2 with IC50 of <0.1 μM and < 1 μM, and has EC50 for HCT116 cells of < 1 μM. |
| PC-26950 |
NCGC00029283
WRN inhibitor
|
NCGC00029283 is a specific small molecule inhibitor of Werner Syndrome helicase-nuclease (WRN) with IC50 of 2.3 uM, 12.5 uM and 3.4 uM for WRN, BLM and FANCJ. |
| PC-26135 |
ART5537
EXO1 inhibitor
|
ART5537 (ART-5537) is highly potent and selective inhibitor of Exonuclease 1 (EXO1) with IC50 of 3.4 nM, inhibits homologous recombination (HR) with EC50 of 7.2 nM in HR reporter assays. |
