Cat. No. |
Product Name |
Information |
PC-38112 |
BMS-820132
|
BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM. |
PC-36020 |
TTP399
GK activator
|
Cadisegliatin (TTP399) is a hepatoselective, oral Glucokinase (GK) activator with EC50 of 304 nM and 762 nM for human GK at high glucose concentration (15 mM) and normoglycemia (5 mM), respectively. |
PC-61879 |
MK-0941 mesylate
|
MK-0941 mesylate (MK0941) is a novel potent, orally active Glucokinase (GK) activator with EC50 of 0.240 and 0.065 uM in 2.5 and 10 mM glucose, respectively. |
PC-61878 |
MK-0941
|
MK-0941 (MK0941) is a novel potent, orally active Glucokinase (GK) activator with EC50 of 0.240 and 0.065 uM in 2.5 and 10 mM glucose, respectively. |
PC-60040 |
Dorzagliatin
|
Dorzagliatin (HMS-5552, HMS5552) is a novel potent, fourth-generation glucokinase (GK) activator. |
PC-42091 |
AM-2394
Glucokinase activator
|
A potent, orally bioavailable Glucokinase (GK) activator with EC50 of 60 nM. |
PC-49838 |
TMG-123
Glucokinase activator
|
TMG-123 (TMG123) is a potent small molecule activator of glucokinase (GK) with EC50 of 0.35 and 0.32 uM for human liver and pancreas GK, respectively. |
PC-49837 |
GKM-001
Glucokinase activator
|
GKM-001 is a potent, liver-selective small molecule activator of glucokinase (GKA), demonstrates glucose lowering effect without hypoglycemia in normal and type II diabetes mellitus (T2DM). |
PC-49836 |
LY2608204
Glucokinase activator
|
Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes. |
PC-49835 |
PF-04937319
Glucokinase activator
|
PF-04937319 (PB-201, PF 4937319) is a partial, pancreas/liver-dual glucokinase activator with EC50 of 174 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes. |
PC-49834 |
AMG 151
Glucokinase activator
|
AMG 151 (ARRY-403) is an orally available allosteric glucokinase activator developed for the treatment of diabetes. |
PC-49828 |
GKA23
Glucokinase activator
|
GKA23 is a potent, small molecule glucokinase (GK) activator with EC50 of 152 nM for glucokinase activation in 5 mM glucose, increases glucose uptake in primary rat hepatocytes with EC50 of 201 nM. |