| Cat. No. |
Product Name |
Information |
| PC-20252 |
Bulevirtide
HBV entry inhibitor
|
Bulevirtide (Myrcludex B, MyrB) is an acylated peptide derived from the large HBV envelope protein, inhibits virus entry and infection. |
| PC-49333 |
GST-HG121
HBV antigen inhibitor
|
GST-HG131 is a specific small molecule HBV antigen inhibitor, exhibits excellent and specific HBV antigens inhibition with EC50 of 28.2 nM (HBsAg) and 16.0 nM (HBeAg), respectively. |
| PC-38680 |
Firzacorvir
HBV inhibitor
|
Firzacorvir (ABI-H2158) is a novel potent HBV core inhibitor structurally distinct from other core inhibitors, ABI-H2158 is a pan-genotypic HBV inhibitor with EC50s ranging from 7.1 to 22 nM across HBV genotypes A-E. |
| PC-38657 |
ZINC20451377
HBsAg inhibitor
|
ZINC20451377 is a small molecule that binds to hepatitis B surface antigen (HBsAg) with high affinity (Kd=65.3 nM), reduces HBsAg levels and HBV virion secretion in cell culture model for HBV. |
| PC-38419 |
Rencofilstat
Cyclophilin inhibitor
|
Rencofilstat (CRV431) is a non-immunosuppressive analogue of cyclosporine A and pan-cyclophilin inhibitor, potently inhibits cyclophilin isoforms A, B, D, and G with IC50 of 1-7 nM. |
| PC-73427 |
Linvencorvir
HBV inhibitor
|
Linvencorvir (RG7907, RG-7907) is an anti-HBV agent, functions as a HBV capsid assembly inhibitor. |
| PC-72718 |
AB-452
PAPD5/7 inhibitor
|
AB-452 (AB452) is a potent, small molecule inhibitor of noncanonical poly(A) polymerases PAPD5 and PAPD7 (PAPD5/7), inhibits PAPD5/7 enzymatic activities, reduces HBsAg in vitro (EC50=1.4/6.8 nM). |
| PC-72677 |
AB-506
HBV core protein inhibitor
|
AB-506 is a small-molecule inhibitor targeting HBV core protein, inhibits viral replication in vitro (IC50=77 nM). |
| PC-72258 |
RG7834
HBV gene expression inhibitor
|
RG7834 (RG-7834, RO7020322) is a potent, specific, orally bioavailable small molecule inhibitor of HBV gene expression, reduces HBV total mRNA levels with EC50 of 5.87 nM. |
| PC-35873 |
NVR 3-778
|
NVR 3-778 (NVR3-778, NVR 3778) is a small molecule inhibitor of HBV replication that targets the viral core protein, a first-in-class capsid assembly modulator. |
| PC-35254 |
GLP-26
|
GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM. |
| PC-35216 |
JNJ-632
|
JNJ-632 (JNJ632) is a novel potent HVV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D. |
