| Cat. No. |
Product Name |
Information |
| PC-38561 |
ATI-2173
HBV inhibitor
|
ATI-2173 is a novel liver-targeted prodrug of clevudine, ATI-2173 is a selective inhibitor of HBV with EC50 of 1.31 nM in primary human hepatocytes with minimal to no toxicity. |
| PC-35638 |
NTCP binder peptide WD1
|
NTCP binder peptide WD1 is a macrocyclic peptide, pan-genotypic inhibitor of HBV cellular entry via targeting the cell-surface receptor for HBV, sodium taurocholate cotransporting polypeptide (NTCP, Kd=15 nM), reduces HBs antigen levels in culture supernatants. |
| PC-35637 |
NTCP binder peptide WL4
|
NTCP binder peptide WL4 is a macrocyclic peptide, pan-genotypic inhibitor of HBV cellular entry via targeting the cell-surface receptor for HBV, sodium taurocholate cotransporting polypeptide (NTCP, Kd=42 nM), reduces HBs antigen levels in culture supernatants with IC50 of 0.66 uM. |
| PC-63406 |
HAP-12
|
HAP-12 is a small molecule HBV capsid assembly effector that inhibits HBV DNA replication with EC50 of 0.5 uM.. |
| PC-63405 |
IR415
|
IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease. |
| PC-63404 |
HBV Capsid inhibitor 3711
|
HBV Capsid inhibitor 3711 (Compound 3711) is a nonnucleosidic HBV inhibitor, inhibits hepatitis B virus replication by inducing genome-free capsid formation. |
| PC-63403 |
BCM-599
|
BCM-599 is an efficient HBV capsid assembly inhibitor with in vitro IC50 of 13 uM, shows synergistic inhibitory effects on decreasing viral concentration combined with lamivudine in vivo.. |
| PC-63329 |
Isothiafludine
|
Isothiafludine (NZ-4) is a novel HBV capsid assembly inhibitor that inhibits HBV replication through blocking pregenomic RNA encapsidation, suppresses HBV replication in HepG2.2.15 cells with IC50 of 1.33 uM. |
| PC-63328 |
HEC72702
|
HEC72702 is a novel potent, orally active inhibitor of HBV capsid assembly, inhibits HBV-DNA levels in HepG.2.2.15 cells with IC50 of 39 nM. |
| PC-63285 |
Besifovir
|
Besifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).. |
| PC-62578 |
RO6889678
|
RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.. |
| PC-42041 |
Bay 41-4109 racemate
|
The racemate form of Bay 41-4109, which is a potent, non-nucleosidic inhibitor of HBV nucleocapsid maturation with IC50 of 0.05 uM.. |
