| Cat. No. |
Product Name |
Information |
| PC-25163 |
Exifone
HDAC1 activator
|
Exifone is a potent activator of the deacetylase activity of HDAC1, increases the rate of deacetylation by the enzyme with EC50 of 0.241 uM and EC1.5 value of 0.031 uM. |
| PC-25162 |
Chlopynostat
HDAC1 inhibitor
|
Chlopynostat is a potent, selective HDAC1 inhibitor with IC50 of 67 nM, with no activity against HDAC6/8/10 (IC50>1000 nM). |
| PC-25161 |
CBUD-1001
HDAC1 inhibitor
|
CBUD-1001 is specific small molecule HDAC1 inhibitor with IC50 of 28.1 nM, inhibits HDAC2 and HDAC3 with IC50 values of 158 nM and 404 nM, respectively. |
| PC-25122 |
Dual Hsp90-HDAC6 inhibitor 17
Hsp90/HDAC6 inhibitor
|
Dual Hsp90/HDAC6 inhibitor 17 is a potent, selective dual Hsp90/HDAC6 inhibitor with IC50 of 28/96 nM respectively. |
| PC-25111 |
Martinostat hydrochloride
HDAC inhibitor
|
Martinostat hydrochloride is a potent, selective inhibitor for class I and class-IIb HDACs with IC50 of 0.3/2.0/0.6 nM for HDAC1/2/3 and 4.1 nM for HDAC6 respectively, >100-fold selectivity over other HDAC isoforms. |
| PC-24898 |
TNI-97
HDAC6 inhibitor
|
TNI-97 is a potent, highly selective and orally bioavailable HDAC6 inhibitor with IC50 of 0.2 nM. |
| PC-24776 |
ITF3107
HDAC6 inhibitor
|
ITF3107 is a potent, selective HDAC6 inhibitor with IC50 of 5 nM, >70-fold more selective for HDAC6over HDAC1/2/3. |
| PC-24775 |
ACY-1083
HDAC6 inhibitor
|
ACY-1083 is a potent, selective and brain-penetrating HDAC6 inhibitor with IC50 of 3 nM, >250-fold more selective for HDAC6 than all other classes of HDAC isoforms. |
| PC-24774 |
ITF3985
HDAC6 inhibitor
|
ITF39856 (ITF-3985) is a potent, selective HDAC6 inhibitor with IC50 of 5 nM, >500-fold selective over HDAC1/2/3. |
| PC-24773 |
ITF3756
HDAC6 inhibitor
|
ITF3756 (ITF-3756) is a potent, selective HDAC6 inhibitor with IC50 of 17 nM, >80-fold selective versus HDAC8 and HDAC Class IIa isoforms (HDAC4, 5, 7, and 9). |
| PC-24769 |
Bavarostat
HDAC6 inhibitor
|
Bavarostat (EKZ-001) is a potent, selective HDAC6 inhibitor with IC50 of 60 nM, 16000-fold selectivity over HDAC1, HDAC2, and HDAC3. |
| PC-24736 |
WMJ-J-09
HDAC inhibitor
|
WMJ-J-09 a potent, hydroxamate based HDAC inhibitor, exhibits potent inhibitory activity against class I HDACs, including HDAC1 (IC50=7.5 nM), HDAC2 (IC50=21.3 nM), HDAC3 (IC50=18.4 nM), and HDAC8 (IC50=90.9 nM), also strongly inhibitsHDAC6 (class IIb) with IC50 of 3.9 nM. |
