Cat. No. |
Product Name |
Information |
PC-35932 |
SW-100
|
SW-100 (SW100) is a potent, selective, brain penetrable HDAC6 inhibitor with IC50 of 2.3 nM, displays >1,000-fold selectivity over all other class I, II, and IV HDAC isoforms. |
PC-35827 |
CHDI-390576
class IIa HDAC inhibitor
|
CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor with IC50 of 54/60/31/50 nM for HDAC4/5/7/9, respectively. |
PC-35344 |
Tucidinostat
|
Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively. |
PC-35170 |
FT895
HDAC11 inhibitor
|
FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM). |
PC-43451 |
Tubastatin A
HDAC6 inhibitor
|
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in cell-free assays. |
PC-43450 |
Tubastatin A hydrochloride
|
Tubastatin A hydrochloride is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in cell-free assays. |
PC-63389 |
GSK-3117391
|
GSK-3117391 (ESM-HDAC391, CHR-5154) is an orally active, myeloid-targeted histone deacetylase (HDAC) inhibitor with IC50 of 55 nM in a HeLa cell nuclear extract fluorometric assay, potently inhibits Class I, Class IIb and Class IV members (HDAC 1/2/3/8, HDAC6/10, and HDAC 11, respectively), with Class IIa enzymes (HDAC4/5/7/9) unaffected. |
PC-63292 |
Marbostat-100
HDAC6 inhibitor
|
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM, displays >200-fold selectivity over HDAC1-5, and HDAC7-10. |
PC-43291 |
NCH-51
HDAC inhibitor
|
NCH-51 is the S-isobutyryl prodrug of NCH-31, which is a potent HDAC inhibitor with IC50 of 48 nM for HDAC1, inhibits cell proliferation of NCI-H460 and MDA-MB-231 with IC50 of 2.1 and 4.4 uM. |
PC-62518 |
Corin
|
Corin is a dual action LSD1/HDAC inhibitor (IC50=0.33/0.20 uM) that potently targets the CoREST complex and shows more sustained inhibition of CoREST complex HDAC activity compared with entinostat. |
PC-62401 |
BRD3308
|
BRD3308 is a potent, selective HDAC3 inhibitor with IC50 of 54 nM, displays >20-fold selectivity over HDAC1 and HDAC2, >500-fold selectivity over other HDAC isoforms. |
PC-61957 |
OBP-801
|
OBP-801 (YM 753;Spiruchostatin A) is a novel cyclic-peptide-based HDAC inhibitor with IC50 of 2 nM. |