Cat. No. |
Product Name |
Information |
PC-49533 |
JG-2016
HAT1 inhibitor
|
JG-2016 is a small molecule inhibitor of histone acetyltransferase 1 (HAT1) with IC50 of 14.8 uM in the HAT1 acetylation assays. |
PC-72790 |
IMP-1575
HHAT inhibitor
|
IMP-1575 (IMP1575) is a potent, selective Hedgehog acyltransferase (HHAT) inhibitor with Ki/IC50 of 38 nM/0.75 uM (Acyl-cLIP assay). |
PC-72712 |
ENL YEATS Domain inhibitor 7
ENL YEATS Domain inhibitor
|
ENL YEATS Domain inhibitor 7 is a selective, small molecule inhibitor of ENL YEATS Domain with IC50 of 0.62 uM in inhibiting the ENL-acetyl-H3 interaction. |
PC-72392 |
PF-9363
KAT6A/6B inhibitor
|
PF-9363 (CTx-648) is a first-in-class, potent and selective KAT6A/6B inhibitor with Ki of 0.41 nM and 1.2 nM for KAT6A and KAT6B, respectively. |
PC-72238 |
NU9056
Tip60 (KAT5) inhibitor
|
NU9056 (NU 9056) is a specific Tip60 (KAT5) histone acetyltransferase inhibitor with IC50 of <2 uM. |
PC-38289 |
WM-3835
HBO1 (KAT7) inhibitor
|
WM-3835 (WM 3835) is a potent, high-specific, cell-permeable inhibitor of MYST acetyltransferase HBO1 (KAT7 or MYST2). |
PC-38126 |
CCS1477
p300/CBP inhibitor
|
CCS1477 (Inobrodib) is an orally bioavailable, potent, and selective inhibitor of the p300/CBP bromodomain, binds to p300 and CBP with Kds of 1.3 and 1.7 nM respectively. |
PC-36166 |
TTK21
CBP/p300 inhibitor
|
TTK21 (CBP-p300 activator TTK21) is a small molecule activator of CBP/p300 histone acetyltransferase activity with a maximal effect at a concentration of 275 uM. |
PC-35580 |
WM-1119
KAT6A inhibitor
|
WM-1119 (WM1119) is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 2 nM, shows greate bioavailability and specificity for KAT6A than WM-8014. |
PC-35579 |
WM-8014
KAT6A inhibitor
|
WM-8014 (WM8014) is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 5 nM and IC50 of 8 nM. |
PC-35322 |
CPTH2
GCN5 inhibitor
|
CPTH2 is a specific histone acetyltransferase inhibitor modulating Gcn5 network in vitro and in vivo, inhibits H3 acetylation and induces cell-cycle perturbation and apoptosis in U-937 cells. |
PC-35321 |
CPTH6 hydrobromide
GCN5/PCAF inhibitor
|
CPTH6 hydrobromide is a thiazole derivative that can reduce histone acetylation and histone acetyltransferase (HAT) activity in human leukemia cells, CPTH6 is a specific Gcn5/pCAF inhibitor. |