| Cat. No. |
Product Name |
Information |
| PC-72225 |
FTO-02
FTO inhibitor
|
FTO-02 is a potent, selective, competitive small molecule inhibitor of m6A-RNA demethylase FTO with IC50 of 2.18 uM, 40-fold selectivity over RNA demethylase ALKBH5 (ALKBH5, IC50=85.5 uM). |
| PC-62978 |
L-α-Hydroxyglutaric acid disodium salt
|
L-α-Hydroxyglutaric acid disodium salt (L-2-Hydroxyglutarate. |
| PC-62840 |
LSD1-IN-11p
|
LSD1-IN-11p is a reversible LSD1 inhibitor with IC50/Kd of 79/21 nM. |
| PC-62837 |
KDM4D-IN-10r
|
KDM4D-IN-10r is a potent, selective histone lysine demethylase 4D (KDM4D) inhibitor with IC50 of 0.41 uM. |
| PC-62835 |
KDM5A-IN-50
|
KDM5A-IN-50 is a potent, selective, and orally bioavailable pan KDM5 enzyme inhibitor with biochemical IC50 of 45/56/55 nM for KDM5A/KDM5B/KDM5C respectively. |
| PC-61815 |
KDM-IN-6
|
KDM-IN-6 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM,respectively. |
| PC-61732 |
LSD1-IN-32
|
LSD1-IN-32 is a potent, reversible lysine specific demethylase 1 (LSD1) inhibitor with biochemical IC50 of 83 nM, Kd of 32 nM, cell EC50 of 0.67 uM. |
| PC-61644 |
LSD1 inhibitor-1
|
LSD1 inhibitor-1 is a bisguanidine polyamine analogue that exhibits noncompetitive and specific LSD1 inhibition, with 14.1% remaining LSD1 activity at 10 uM in vitro. |
| PC-42195 |
D-alpha-Hydroxyglutaric acid disodium salt
|
A competitive inhibitor of multiple α-KG-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases. |
