| Cat. No. |
Product Name |
Information |
| PC-26437 |
DC551040 dihydrochloride
LSD1 inhibitor
|
DC551040 dihydrochloride is a potent, selective, irreversible and orally bioavailable LSD1 inhibitor with IC50 of 2.14 nM. |
| PC-26423 |
TAS1440
LSD1 inhibitor
|
TAS1440 (TAS-1440) is a potent, selectve, histone H3-competitive non-covalent LSD1 inhibitor with IC50 of 4.8 nM, disrupts INSM1-LSD1 complex activating tumor-suppressive pathways. |
| PC-25883 |
JMJD6 inhibitor 7p
JMJD6 inhibitor
|
JMJD6 inhibitor 7p is potent, selective JMJD6 inhibitor with IC50 of 681 nM, shows no activity against other JmjC domain-containing protein family members. |
| PC-25582 |
Methylstat
JHDMs inhibitor
|
Methylstat is a selective inhibitor of Jumonji C domain-containing histone demethylases (JHDMs) in cells, preferentially inhibits JMJD2A (H3K9me3 and H3K36me3 demethylase), JMJD2E (H3K9me3 demethylase) and JMJD3 (H3K27me3 demethylase). |
| PC-24718 |
Tranylcypromine hydrochloride
LSD1 inhibitor
|
Tranylcypromine (SKF385) hydrochloride is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1, KDM1A) and monoamine oxidase (MAO), inhibits LSD1, MAO-A and MAO-B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. |
| PC-24469 |
FTO inhibitor F97
FTO inhibitor
|
F97 is a specific small molecule inhibitor of fat mass and obesity-associated protein (FTO) with IC50 of 0.45 uM, selectively inhibits m6A demethylation by FTO rather than ALKBH5, and has minimal effect on m1A demethylation by ALKBH3. |
| PC-24227 |
GSK690 hydrochloride
LSD1 inhibitor
|
GSK690 hydrochloride is a potent, reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM. |
| PC-24023 |
ALKBH5 inhibitor 18l
ALKBH5 inhibitor
|
ALKBH5 inhibitor 18l is a potent, selective, covalent inhibitor of N6-methyladenosine (m6A) demethylase ALKBH5 with Kd of 804 nM, IC50 of 0.62 uM. |
| PC-24003 |
JBI-097
LSD1/HDAC6 inhibitor
|
JBI-097 is a potent, dual LSD1/HDAC6 inhibitor with IC50 of 6/48 nM respectively, also inhibits HDAC8 (IC50=71 nM), does not inhibit other HDACs. |
| PC-24002 |
LH-1802
LSD1 inhibitor
|
LH1802 is a potent, selective and reversible inhibitor of lysine-specific demethylase 1 (LSD1) with EC50 of 470 nM (CD86). |
| PC-24000 |
CBB1007
LSD1 inhibitor
|
CBB1007 is a cell-permeable, potent, reversible and substrate competitive LSD1 selective inhibitor with IC50 of 5.27 uM. |
| PC-23999 |
CBB1003
LSD1 inhibitor
|
CBB1003 is a novel lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 10.54 uM. |
