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Cat. No. Product Name Information
PC-21915

ALKBH1 inhibitor 13h

ALKBH1 inhibitor

ALKBH1 inhibit 13h is a potent, isoform selective, and cell-active DNA 6mA demethylase ALKBH1 inhibitor with 26 nM and 1.39 uM in FP and enzyme activity assay, respectively.
PC-21875

WS-384

LSD1 inhibitor

WS-384 is a specific, small-molecule inhibitor dually targeting LSD1 (IC50=338.8 nM) and the DCN1-UBC12 interaction (IC50=14.8 uM).
PC-21840

P3FI-90

KDM3B inhibitor

P3FI-90 is a specific small molecule inhibitor of KDM3B with SPR KD of 7.68 uM, inhibits PAX3-FOXO1 activityand blocks PAX3-FOXO1 downstream target gene expression.
PC-21777

JMJD1C inhibitor 193D7

JMJD1C inhibitor

193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.
PC-21684

iPHF8

PHF8 inhibitor

iPHF8 (inhibitor of PHF8) is a specific inhibitor of protein demethylase PHF8 with IC50 of 2.01 uM in Succinate-Glo JmjC demethylase assays, and SPR KD value of 240 nM.
PC-21211

GSK-J4

KDM6A/6B inhibitor

GSK-J4 is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 μM, respectively, GSK-J4 s a cell permeable prodrug of GSK-J1.
PC-21085

JMJD5 inhibitor 19j

JMJD5 inhibitor

JMJD5 inhibitor 19j is a potent selective small molecule inhibitor of 2OG-dependent oxygenase JMJD5 (KDM8), shows high selectivity over other human 2OG oxygenases.
PC-20876

ZY0511

LSD1 inhibitor

ZY0511 is a highly selective and potent inhibitor of lysine‐specific histone demethylase 1 (LSD1) with IC50 of 1.7 nM and SPR Kd of 2.42 nM.
PC-20519

TAK-418

LSD1 (KDM1A) inhibitor

TAK-418 (TAK418) is a potent, specific inhibitor of LSD1 (KDM1A) enzyme activity with IC50 of 2.9 nM.
PC-20355

KDM5B inhibitor 27ab

KDM5B inhibitor

KDM5B inhibitor 27ab is a potent inhibitor of histone lysine specific demethylase 5B (KDM5B/JARID1B) with IC50 of 24.4 nM.
PC-20354

KDM5A inhibitor compound 1

KDM5A inhibitor

KDM5A inhibitor compound 1 (ZINC33576) is a potent, selective KDM5A (JARID1A) inhibitor with IC50 of 23.8 nM.
PC-20352

EPZ020809

KDM4C inhibitor

EPZ020809 is a potent, specific KDM4C inhibitor with Ki of 31 nM, binds KDM4C in a 2-OG-competitive fashion.

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