| Cat. No. |
Product Name |
Information |
| PC-61690 |
FF-10501-01
|
FF-10501-01 is a potent, selective and orally available IMPDH inhibitor. |
| PC-49656 |
AVN-944
Molecular Weight:
|
AVN-944 (VX-944) is a potent, selective, noncompetitive inhibitor of both human inosine 5-monophosphate dehydrogenase (IMPDH) isoforms (Ki=6-10 nM). |
| PC-49653 |
FF-10501
IMPDH inhibitor
|
FF-10501 (SM-108) is a small molecule inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), maintained cell growth inhibitory activities in the azacitidine-resistant cell lines. |
| PC-35012 |
VX-148
|
VX-148 is a potent, uncompetitive, orally bioavailable IMPDH inhibitor with Ki of 6 nM against IMPDH type II enzyme. |
| PC-35011 |
Merimepodib
|
Merimepodib (VX-497, VI-21497, MMPD) is a potent, selective, reversible, uncompetitive IMPDH inhibitor with broad-spectrum antiviral activity. |
| PC-70216 |
Sappanone A
|
A homoisoflavanone found in Caesalpinia sappan, a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with Kd of 3.944 nM, almost 10 times lower than the Kd of binding to IMPDH1. |
| PC-70215 |
IMPDH2-IN-5
|
A potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production). |
