| Cat. No. |
Product Name |
Information |
| PC-63079 |
BMS-986126
IRAK4 inhibitor
|
BMS-986126 is a potent, highly selective inhibitor of IRAK4 kinase with IC50 of 5.3 nM, displays >100-fold selective for IRAK4 over a panel of 214 kinases. |
| PC-61623 |
IRAK4 inhibitor 23
IRAK4 inhibitor
|
IRAK4 inhibitor 23 is a potent, selective, orally bioavailable IRAK4 inhibitor with IC50 of 7 nM. |
| PC-61092 |
PF-05387252
IRAK4 inhibitor
|
A potent, selective IRAK4 inhibitor with IC50 of 1.3 nM, 200-fold selectivity over IRAK1 (IC50=290 nM). |
| PC-61091 |
PF-05388169
IRAK4 inhibitor
|
PF-05388169 is a potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM). |
| PC-60997 |
AS2444697
IRAK4 inhibitor
|
AS2444697 is a potent, selective, orally bioavailable IRAK4 inhibitor (IC50=21 nM), potently inhibits human and rat IRAK-4 activity with subnanomolar order, >30-fold selectivity over IRAK-1. |
| PC-60980 |
IRAK4-IN-16
IRAK4 inhibitor
|
IRAK4-IN-16 is a potent, selective, and orally bioavailable inhibitor of interleukin-1 receptor-associate kinase-4 (IRAK4) with IC50 of 2.8 nM, 217- and 892-fold selectivity over IRAK-1 and TAK1, respectively. |
| PC-50002 |
Emavusertib
IRAK4 inhibitor
|
Emavusertib (CA4948, AU4948) is a potent, selective and orally active IRAK4 inhibitor with IC50 of 31.7 nM. |
| PC-70009 |
Thymoquinone
IRAK1 inhibitor
|
Thymoquinone is an anticancer phytochemical commonly found in black cumin, exhibits anticancer activity via numerous mechanisms of action, specifically by showing selective antioxidant and oxidant activity. |
| PC-60013 |
AZ1495
IRAK4 inhibitor
|
AZ1495 is a potent, selective IRAK4 inhibitor with IC50 of 51 nM. |
| PC-45740 |
PF-06650833
IRAK4 inhibitor
|
Zimlovisertib (PF-06650833) is a potent and selective IRAK4 inhibitor with IC50 of 0.2 nM. |
| PC-27484 |
Odemsertib etifosfate
IRAK inhibitor
|
Odemsertib etifosfate is a potent, selective IRAK inhibitor. |
| PC-26786 |
UR241-2
IRAK4 inhibitor
|
UR241-2 is a potent and selective IRAK4 inhibitor with IC50 of 1.93 nM in HotSpot Kinase assays, inhibits NF-κβ nuclear translocation and blocks IL-1β–induced IRAK4 phosphorylation. |
