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Cat. No. Product Name Information
PC-61091

PF-05388169

A potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM).
PC-60997

AS 2444697

A potent, selective, orally bioavailable IRAK-4 inhibitor that potently inhibits human and rat IRAK-4 activity with subnanomolar order, >30-fold selectivity over IRAK-1.
PC-60980

IRAK4-IN-16

A potent, selective, and orally bioavailable inhibitor of interleukin-1 receptor-associate kinase-4 (IRAK4) with IC50 of 2.8 nM, 217- and 892-fold selectivity over IRAK-1 and TAK1, respectively.
PC-70009

Thymoquinone

An anticancer phytochemical commonly found in black cumin.
PC-60013

IRAK4-IN-28

A novel potent, selective IRAK4 inhibitor with IC50 of 51 nM.

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