| Cat. No. |
Product Name |
Information |
| PC-20487 |
JZL195
Dual MAGL/FAAH inhibitor
|
JZL195 (JZL 195) is a potent, selective dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC50s of 2 and 4 nM, respectively. |
| PC-49167 |
MAGLi 432
MAGL inhibitor
|
MAGLi 432 is a highly selective, potent and reversible monoacylglycerol lipase (MAGL) inhibitor with IC50 of 4.2 and 3.1 nM for human and mouse MAGL enzyme, respectively. |
| PC-73016 |
AM6580
MAGL covalent inhibitor
|
AM6580 is a potent, covalent monoacylglycerol lipase (MAGL) inhibitor with IC50 of 3 nM (hMAGL). |
| PC-73012 |
AM9928
MAGL covalent inhibitor
|
AM9928 is a potent, covalent monoacylglycerol lipase (MAGL) inhibitor with IC50 of 8.9 nM (hMAGL). |
| PC-35522 |
ABX-1431
|
Elcubragistat (ABX1431) is a highly potent, selective, orally available, CNS-penetrant monoacylglycerol lipase (MGLL) with IC50 of 14 nM (hMGLL). |
| PC-60707 |
MJN110
MAGL inhibitor
|
MJN110 (MJN-110) is a potent, selective, and orally active MAGL inhibitor with IC50 of 2.1 nM (2-AG hydrolysis). |
| PC-60701 |
JJKK-048
|
JJKK-048 (JJKK048) is a potent, highly selective monoacylglycerol lipase (MAGL) with IC50 of <0.4 nM against human and rodent MAGL. |
| PC-42260 |
URB602
|
URB602 is a selective, noncompetitive monoacylglycerol lipase (MAGL) inhibitor with IC50 of 28 uM against rat brain MAGL. |
| PC-45584 |
KML-29
|
KML-29 is a potent, highly selective MAGL (monoacylglycerol lipase) inhibitor with IC50 of 15 nM. |
| PC-20488 |
AKU-005
Dual MAGL/FAAH inhibitor
|
AKU-005 is a potent, dual MAGL/FAAH inhibitor with IC50 of 589 and 309 pM for MAGL in rat and mouse brain membrane respectively, inhibits rat and human FAAH with IC50 of 63 and 389 nM. |
| PC-20486 |
JZL184
MAGL inhibitor
|
JZL184 (JZL 184) is a potent, selective and irreversible MAGL inhibitor, blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes with IC50 of 8 nM, >300-fold selectivity for MAGL over FAAH. |
| PC-72112 |
JNJ-42226314
MAGL inhibitor
|
JNJ-42226314 (JNJ42226314) is a potent, highly selective and reversible MAGL inhibitor with IC50 of 1.13 nM (hMAGL). |
