| Cat. No. |
Product Name |
Information |
| PC-45953 |
D609
PC-PLC inhibitor, SMS inhibitor
|
D609 is a competitive inhibitor of PC-PLC with Ki of 6.4 uM, also is a small molecule of sphingomyelin synthase (SMS1 and SMS2). |
| PC-26186 |
Melittin
PLA2 activator
|
Melittin is a peptide phospholipase A2 (PLA2) activator, stimulates the activity of the low molecular weight PLA2, does not the increase activity of the high molecular weight PLA2. |
| PC-26014 |
BRI-50460
cPLA2 inhibitor
|
BRI-50460 is a potent, selective and brain-penetrant cytosolic calcium-dependent phospholipase A2 (cPLA2) inhibitor with IC50 of 0.88 nM for cellular arachidonic acid (AA) release and 4.1 nM for downstream PGE2 production. |
| PC-25982 |
AACOCF3
cPLA2 inhibitor
|
Arachidonyl trifluoromethyl ketone (AACOCF3) is an arachidonic acid analog and potent and selective, slow- and tight-binding inhibitor of cytosolic phospholipase A2 (cPLA2), inhibits the release of AA from calcium ionophore-challenged U937 cells (IC50= 8 uM) and from platelets (IC50=2 uM). |
| PC-25738 |
ONO-RS-082
PLA2 inhibitor
|
ONO-RS-082 is a specific phospholipase A2 (PLA2) inhibitor with IC50 of 1.0 uM, does not inhibit PKC. |
| PC-24356 |
ABD778
ABHD17 inhibitor
|
ABD778 is a potent and selective, in vivo-active ABHD17 inhibitor with IC50 of 76 nM and 84 nM for both human and mouse ABHD17 enzymes, respectively, is the isopropyl ester analog of ABD957. |