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Cat. No. Product Name Information
PC-38430

Zastaprazan

Gastric H+/K+-ATPase inhibitor

Zastaprazan (JP-1366) is a potent selective inhibitor of gastric H+/K+-ATPase activity with IC50 of 16.7 nM, >400-fold selectivity over Na+/K+-ATPase activity.
PC-38295

2GBI

Hv1 channel inhibitor

2GBI (2-guanidinobenzimidazole) is a guanidine derivative that inhibits voltage-gated proton channel Hv1 by binding to the VSD from its intracellular side..
PC-38294

YHV98-4

Hv1 channel inhibitor

YHV98-4 is a selective inhibitor of proton-selective ion channel Hv1 with IC50 of 0.7 uM.
PC-62141

BRD1240

BRD1240 is a small-molecule probe that can suppress V-ATPase function, inhibits lysosomal acidification and blocks the maturation of autophagosomes to autolysosomes.
PC-60826

TAK-438

TAK-438 (Vonoprazan) is a novel potent, potassium-competitive acid blocker (P-CAB) that inhibits H(+),K(+)-ATPase activity in porcine gastric microsomes with IC50 of 19 nM at pH 6.5.
PC-60811

Tegoprazan

Tegoprazan (CJ 12420, RQ-00000004, RQ-4) is a novel potent, highly selective, competitive and orally active inhibitor of gastric H+/K+-ATPase with IC50 of ranging 0.29-0.52 uM porcine, canine and human H+/K+-ATPases in vitro.
PC-73426

Linaprazan glurate

Proton Pump inhibitor

Linaprazan glurate (X-842) is a proton pump inhibitor with potential for treatment of oesophagitis.
PC-72018

Hv1 inhibitor HIF

Hv1 channel inhibitor

Hv1 inhibitor HIF is a novel inhibitor of the voltage-gated proton channel Hv1 interacts with the Hv1 VSD in the up and down states.
PC-63544

Diphyllin

Diphyllin is a naturally potent vacuolar ATPase (v-ATPase) inhibitor with IC50 of 17 nM, potently inhibits the acid influx with IC50 of 0.6 nM.
PC-62959

AR-HO47108

AR-HO47108 is a potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 7.0.
PC-62893

CS-526

CS-526 (AKU 517.
PC-62892

Revaprazan

Revaprazan (SB-641257.

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