| Cat. No. |
Product Name |
Information |
| PC-35434 |
SINCRO
STING agonist
|
SINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes. |
| PC-35312 |
STING inhibitor H-151
STING inhibitor
|
STING inhibitor H-151 (H151) is a highly potent, selective, covalent small-molecule antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo. |
| PC-35311 |
STING inhibitor C-176
STING inhibitor
|
STING inhibitor C-176 (C176) is a covalent, in vivo-active, small-molecule inhibitor of STING, attenuates STING-associated autoinflammatory disease in mice. |
| PC-35310 |
STING inhibitor C-178
STING inhibitor
|
STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING. |
| PC-62663 |
cGAMP
|
cGAMP is a potent STING activator that binds to hSTING R232 and hSTING A230/R232 with Kd of 0.11 uM and 0.16 uM, respectively. |
| PC-62660 |
2 3-cGAMP
STING agonist
|
2′3′-cGAMP is a potent STING activator that binds to STING with Kd of 1.61 uM. |
| PC-62639 |
ADU-S100
STING agonist
|
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide agonist of STING, elicits potent and durable anti-tumor immunity when administered IT in pre-clinical syngeneic tumor models.. |
| PC-61228 |
STING agonist C11
|
STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells. |
| PC-60186 |
Cridanimod
|
Cridanimod (10-carboxymethyl-9-acridanone, 10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-45676 |
STING Agonist-1
|
G10 (STING Agonist 1) is a novel human-specific STING agonist. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-21582 |
NVS-STG2
STING agonist
|
NVS-STG2 is a small molecule STING agonist with AC50 of 5.2 uM in ISRE-Luc reporter assays, induces STING-dependent IRF3 phosphorylation in THP1 cells. |
