| Cat. No. |
Product Name |
Information |
| PC-62663 |
cGAMP
STING agonist
|
cGAMP is a potent STING activator that binds to hSTING R232 and hSTING A230/R232 with Kd of 0.11 uM and 0.16 uM, respectively. |
| PC-62660 |
2 3-cGAMP
STING agonist
|
2′3′-cGAMP is a potent STING activator that binds to STING with Kd of 1.61 uM. |
| PC-62639 |
ADU-S100 disodium salt
STING agonist
|
ADU-S100 (MIW815, ML RR-S2 CDA) disodium salt is a synthetic cyclic dinucleotide derivative that functions as a highly potent agonist of STING, enhances binding affinity to STING and activates all known human STING alleles. |
| PC-61228 |
STING agonist C11
STING agonist
|
STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells. |
| PC-60187 |
Cridanimod sodium
STING agonist
|
Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-60186 |
Cridanimod
STING agonist
|
Cridanimod (10-CMA, XBIO-101, CMA) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-45676 |
STING agonist G10
STING agonist
|
G10 (STING agonist G10) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-26989 |
MSA-2 dimer
STING agonist
|
MSA-2 dimer (diMSA-2) is a selective, orally active non-nucleotide STING agonist with KD of 145 uM, binds to STING as a non-covalent dimer and exhibits long-term antitumor and immunogenic activity. |
| PC-26988 |
Caged-diBSP01
STING agonist
|
Caged-diBSP01 is the first photoactivatable STING agonist diBSP01, can binds to and activate STING at 400 nm irradiation led to the liberation of the parent drug diBSP01. |
| PC-26987 |
diBSP01
STING agonist
|
diBSP01 is a potent dimer agonist of STING, exhibits promising binding properties (ITC KD=218 nM, hSTINGH232 protein) and agonistic potency in vitro. |
| PC-26958 |
DDO-88109
STING inhibitor
|
DDO-88109 is a potent small molecule STING inhibitor with SPR Kd of 317 nM for hSTING-CTDWT, shows broad affinity for hSTING isoforms (WT, HAQ, and H232) and selectively suppresses the activation of cGAS-STING signaling pathway. |
