| Cat. No. |
Product Name |
Information |
| PC-61228 |
STING agonist C11
STING agonist
|
STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells. |
| PC-60187 |
Cridanimod sodium
STING agonist
|
Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-60186 |
Cridanimod
STING agonist
|
Cridanimod (10-CMA, XBIO-101, CMA) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-45676 |
STING agonist G10
STING agonist
|
G10 (STING agonist G10) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-24987 |
STING activator diABZI-a1
STING agonist
|
STING activator diABZI-a1 is a potent, small molecule activator of STING, elicits IFNβ in human PBMCs with EC50 of 117 nM. |
| PC-24986 |
STING inhibitor diABZI-i
STING inhibitor
|
STING inhibitor diABZI-I (STING-IN-6) is a potent, small molecule inhibitor of STING, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 49 nM. |
| PC-24981 |
STING inhibitor 18
STING inhibitor
|
STING inhibitor 18 is a potent, orthosteric STING inhibitor / antagonist with IC50 of 68 nM in HAQ STING cGAMP displacement assay. |
| PC-24980 |
STING inhibitor THIQi
STING inhibitor
|
STING inhibitor THIQi is a potent, orthosteric STING inhibitor with IC50 of 84 nM in HAQ STING cGAMP displacement assays, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 29 nM. |
| PC-24871 |
Clonixeril
STING inhibitor
|
Clonixeril (CXL) is a highly potent, non-nucleotide hSTING modulator, has two modes of interaction with hSTING, shows weak agonist activity at micromolar concentrations, acts as a hSTING antagonist at <1 nM (EC50 < 1fM). |
| PC-24803 |
SR-301
STING agonist
|
SR-301 is a potent, non-nucleotide, oral small-molecule STING agonist with EC50 of 0.6 uM. |
| PC-24802 |
ZSA-215
STING agonist
|
ZSA-215 is a potent oral STING agonist with EC50 of 3.3 uM, enhances STING signaling through promoting the phosphorylation of STING and interferon regulatory factor 3 (IRF3) and secretion of IFN-β. |
