| Cat. No. |
Product Name |
Information |
| PC-21157 |
LB244
STING inhibitor
|
LB244 (LB-244) is a highly potent, selective and irreversible STING antagonist, blocks STING oligomerization and inhibits STING signaling THP1 dual cells with IC50 of 0.8 uM. |
| PC-20989 |
DWL-4-140
STING inhibitor
|
DWL-4-140 is a small molecule inhibitor of cyclized nucleotide-binding domain (CBD) of STING, selectively inhibits DNA-mediated IFNβ responses with IC50 of 617 nM. |
| PC-20020 |
SB24011
STING-TRIM29 inhibitor
|
SB24011 (SB 24011) is a selective small molecule inhibitor of the STING-TRIM29 interaction with IC50 of 3.85 uM in luciferase complementation assays, enhances cGAMP-mediated STING immunity. |
| PC-49595 |
HB3089
STING agonist
|
HB3089 (HB-3089) is a novel potent, highly specific STING agonist, dose-dependently activates interferon-stimulated gene (ISG) signaling in THP1-Dual reporter cells with EC50 of 1-10 uM. |
| PC-49313 |
BSP16
STING agonist
|
BSP16 (LF250) is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer. |
| PC-38565 |
STING inhibitor C-170
STING inhibitor
|
STING inhibitor C-170 is a small-molecule STING inhibitor, efficiently inhibited both hsSTING and mmSTING. |
| PC-73370 |
STING activator Compound 8
STING agonist
|
STING activator Compound 8 is a potent, small molecule activator/agonist of human STING with EC50 of 122 nM (HEK, R232), HAQ STING EC50 of 944 nM. |
| PC-73369 |
STING activator Compound 11
STING agonist
|
STING activator Compound 11 is a potent, small molecule activator/agonist of human STING with EC50 of 66 nM (HEK, R232). |
| PC-73360 |
G140
cGAS inhibitor
|
G140 is a potent, specific human cGAS small-molecule inhibitor with IC50 of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. |
| PC-73356 |
STING agonist 22
STING agonist
|
STING agonist 22 is a novel, non-nucleotide specific small-molecule STING agonist with IC50 of 28, 11 uM for human STING isoforms WT and HAQ, respectively. |
| PC-38079 |
SN-008
|
SN-008 is the negative control compound for STING inhibitor SN-011.. |
| PC-35783 |
STING agonist diABZI compound 2
|
STING agonist diABZI compound 2 is an amidobenzimidazole (ABZI)-based compound that functions as a STING agonist with Kd of 1.6 nM (binding of endogenous full-length STING, THP-1 cell lysates). |
