| Cat. No. |
Product Name |
Information |
| PC-38030 |
VK2809
THRβ agonist
|
VK2809 (MB07811) is a potent, liver-specific thyroid hormone receptor β (THRβ) agonist for development for the treatment of hypercholesterolemia. |
| PC-42920 |
MGL-3196
|
MGL-3196 (VIA-3196, Resmetirom) is a potent and highly selective agonist of THR-β (Thyroid Hormone Receptor β) with EC50 of 0.21 uM. |
| PC-20362 |
QRX-431
TRβ1 agonist
|
QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431) is a TRβ1-selective thyromimetic, selectively binds to TRβ over TRα with Kd values of 0.1 and 1.8 nM, respectively. |
| PC-20361 |
CS27109
THR-β agonist
|
CS27109 is a potent, selective thyroid hormone receptor-β (THR-β) agonist with AC50 value of 1.98 uM, 12.6-fold selectivity over THR-α. |
| PC-35610 |
KB-141
|
KB-141 (KB141) is a potent, selective thyroid hormone receptor TRβ agonist (IC50=1.1 nM), binds to hTRβ with a 14-fold higher affinity than to hTRα. |
| PC-35609 |
MB 07811
|
MB 07811 (MB07811) is an orally bioavailable, liver-targeted prodrug of MB07344, which is a thyroid hormone receptor-beta agonist (TRβ) agonist, efficiently converted to MB07344 by liver microsomes in vivo. |
