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Cat. No. Product Name Information
PC-21370

ETC-6152

UBE2T inhibitor

ETC-6152 is a potent, specific and covalent E2 ubiquitin ligase UBE2T inhibitor with IC50 of 0.22 uM, targets Cys86 of UBE2T and shows selectivity on UBE2T over UBE2K.
PC-73071

UBE2T/FANCL inhibitor UC2

UBE2T/FANCL inhibitor UC2

UBE2T/FANCL inhibitor UC2 (UC2) is a specific small-molecule inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation, inhibits the ubiquitylation of GST-FANCL RINGwith IC50 of 14.8 uM in HTRF ubiquitylation assay.
PC-72869

UC-764865

UBE2N inhibitor

UC-764865 (UC764865) is a small-molecule inhibitor that targeted ubiquitin-conjugating enzyme UBE2N active site.
PC-72868

UC-764864

UBE2N inhibitor

UC-764864 (UC764864) is a small-molecule inhibitor that targeted ubiquitin-conjugating enzyme UBE2N active site.
PC-72230

DI-1548

DCN1 inhibitor

DI-1548 (DI 1548) is a potent, selective and covalent DCN1 inhibitor with IC50 of 4.6 nM and Ki of <1 nM, does not bind to DCN3.
PC-38264

ML307

Ubc13 inhibitor

ML307 is a potent, sub-micromolar (IC50=781 nM), first-in-class, small molecule inhibitor of Ubc13 enzyme activity, >128-fold selective against Caspase-3 and Bfl-1.
PC-36111

WS-383

DCN1 inhibitor

WS-383 (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM.
PC-36110

WS-383 hydrochloride

DCN1 inhibitor

WS-383 hydrochloride (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM.
PC-35686

NSC697923

Ubc13 inhibitor

NSC697923 (NSC 697923) is a small molecule that specifically inhibits the activity of the ubiquitin-conjugating (E2) enzyme Ubc13 (UBE2N)-Uev1A.
PC-35287

C25-140

TRAF6 inhibitor

C25-140 is a specific, first-in-class small molecule inhibitor of the TRAF6-Ubc13 interaction, binds TRAF6, inhibits TRAF6-Ubc13 interaction and TRAF6 activity.
PC-35105

GSK145A

SUMOylation inhibitor

GSK145A is a small molecule inhibitor of SUMO-conjugating enzyme E2 with IC50 of 12.5 uM, GSK145A is competitive with the sumoylation of the TRPS1 peptide substrates..
PC-63291

UBE2M-DCN1 inhibitor 52

DCN1 inhibitor

UBE2M-DCN1 inhibitor 52 is a highly potent inhibitor of DCN1-UBE2M protein-protein interaction with IC50 of 60 nM, inhibits cullin neddylation in pulse-chase NEDD8 transfer assay with EC50 of 80 nM.

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