| Cat. No. |
Product Name |
Information |
| PC-27223 |
Alfuzosin hydrochloride
α1-adrenoceptor antagonist
|
Alfuzosin (SL 77499) hydrochloride is an orally active, selective and competitive α1-adrenoceptor antagonist, shows potential for prostatic hyperplasia (BPH). |
| PC-27222 |
Alfuzosin
α1-adrenoceptor antagonist
|
Alfuzosin (SL 77499) is an orally active, selective and competitive α1-adrenoceptor antagonist, shows potential for prostatic hyperplasia (BPH). |
| PC-27221 |
Doxazosin
α1-adrenoceptor antagonist
|
Doxazosin is a long-lasting, selective antagnist of α1-adrenoceptor antagonist receptors, shows potent apoptotic effect against prostate tumor epithelial cells, also has direct inhibitory effect on cholesterol synthesis independent of the LDL receptor. |
| PC-26994 |
SOM3355
β1-adrenergic receptor antagonist
|
Bevantolol hydrochloride (SOM3355) is a CNS-permeant, selective β1-adrenergic receptor antagonist with pKi value of 7.83 in rat cerebral cortex, also shows additional VMAT2 and VMAT1 inhibition activity. |
| PC-26836 |
Terazosin
PGK1 activator, α1-adrenergic receptor antagonist
|
Terazosin is a small molecule α1-adrenergic receptor antagonist and activator of phosphoglycerate kinase 1 (PGK1) at 2.5 nM -0.5 uM, binds to PGK1 with ITC Kd of 2.78 uM. |
| PC-26658 |
RX821002
α2A/D-adrenoreceptor antagonist
|
RX821002 (2-Methoxyidazoxan) is a highly selective antagonist of alpha2A/D-adrenoreceptor (alpha2A/D-AR) antagonist with pKd of 8.2 and 9.7 for rabbit alpha 2A-adrenoceptor and guinea-pig alpha 2D-adrenoceptor respectively. |
| PC-26581 |
A-61603
α1A AR agonist
|
A-61603 is a potent, selective alpha 1-adrenergic receptor (α1A AR) agonist, >35-fold more potent at α1A than at α1B or α1D sites, induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro with EC50 of 6.9 nM. |
| PC-25621 |
Trifluoperazine
eEF2K inhibitor, α1-adrenergic receptor antagonist
|
Trifluoperazine is an antiadrenergic, antidopaminergic and anticholinergic agent, potent α1-adrenergic receptor antagonist, also inhibits calcium/calmodulin to eEF2K. |
| PC-25616 |
Vatinoxan hydrochloride
α2A adrenoceptor antagonist
|
Vatinoxan hydrochloride (MK-467, L-659066) is a potent and selective alpha-2 adrenoceptor (α2A adrenoceptor, α2AR) antagonist with IC50 of 3 nM against the binding of [3H]rauwolscine to rat cerebrocortical membranes, selective over alpha-1 adrenoceptors. |
| PC-25423 |
Formoterol fumarate
β2-adrenoceptor agonist
|
Formoterol fumarate is a potent, selective and long-acting β2-adrenoceptor agonist. |
| PC-25233 |
Imiloxan hydrochloride
α2B adrenoceptor antagonist
|
Imiloxan hydrochloride (RS 21361) is a potent and selective alpha 2B-adrenoceptor antagonist. |
| PC-25232 |
ADRIANA
α2B adrenoceptor antagonist
|
ADRIANA (c545) is a potent, orally active α2B adrenoceptor subtype-specific antagonist with binding Ki of 987 nM, >50-fold selective over α2A adrenoceptor. |
