| Cat. No. |
Product Name |
Information |
| PC-43903 |
Olodaterol
β2 adrenoceptor agonist
|
Olodaterol (BI 1744) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2. |
| PC-45155 |
Medetomidine
α2-adrenoceptor agonist
|
Medetomidine is a potent, highly selective α2-adrenoceptor agonist with Ki of 1.08 nM. |
| PC-45295 |
Carteolol hydrochloride
Beta-blocker
|
Carteolol hydrochloride is a non-selective beta-adrenoceptor antagonist (Beta-blocker) used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent. |
| PC-45270 |
Salmeterol
β2AR agonist
|
Salmeterol (GR33343X) is a long-acting beta2-adrenergic receptor agonist (Ki=1.5 nM) used clinically to treat asthma and maintenance of COPD. |
| PC-45299 |
Bambuterol hydrochloride
beta-adrenoceptor agonist
|
Bambuterol hydrochloride (KWD-2183) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; also is a prodrug of terbutaline. |
| PC-45298 |
Bambuterol
beta-adrenoceptor agonist
|
Bambuterol is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; also is a prodrug of terbutaline. |
| PC-42338 |
Silodosin
α1A-adrenoceptor antagonist
|
Silodosin (KAD3213, KMD3213) is a highly potent, uroselective α1a-adrenoceptor antagonist with Ki of 36 pM. |
| PC-27379 |
ICI-118551 hydrochloride
β2-adrenergic receptor antagonist
|
ICI-118551 hydrochloride (Zenidolol) is a potent, selective β2-adrenergic receptor (ADRB2, beta(2)-AR) antagonist with Ki of 0.7, 49.5 and 611 nM for β2, β1 and β3 adrenergic receptors respectively. |
| PC-27378 |
ICI-118551
β2-adrenergic receptor antagonist
|
ICI-118551 (Zenidolol) is a potent, selective β2-adrenergic receptor (ADRB2, beta(2)-AR) antagonist with Ki of 0.7, 49.5 and 611 nM for β2, β1 and β3 adrenergic receptors respectively. |
| PC-27361 |
Dexmedetomidine
α2-adrenoceptor agonist
|
Dexmedetomidine is a potent, selective agonist of α2-adrenergic receptor (α2-adrenoceptor) with Ki of 1.08 nM, >1000-fold selectivity against α1-adrenoceptor. |
| PC-27360 |
Tizanidine
α2-adrenoceptor agonist
|
Tizanidine is a skeletal muscle relaxant and an orally effective central α2-adrenoceptor agonist (IC50=6 nM), exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons, also inhibits the proliferation, migration, and invasion of lung cancer cells. |
| PC-27359 |
CC10137
α2AAR agonist
|
CC10137 is a potent, orally bioavailable, peripherally restricted α2A-adrenergic receptor (α2AAR) agonist with Ki of 6.0 nM, exhibits potent α2AAR agonist activity (EC50=13.1 nM) in HEK293T cells co-transfected with α2AAR and Gα15 plasmids. |
