| Cat. No. |
Product Name |
Information |
| PC-49727 |
YTK-2205
p62 agonist, autophagy inducer
|
YTK-2205 (YTK2205) is a small molecule p62 agonist targeting ZZ domain, induces selective autophagy activation, YTK-2205 augments the translocation of p62 to mitochondria, targeting their lysosomal degradation. |
| PC-49174 |
EAD1
Autophagy inhibitor
|
EAD1 is a potent autophagy inhibitor, exhibits growth inhibitory activity in human cancer cell lines, H460 and HCC827 NSCLC and BxPC3 pancreatic cancer cells with IC50 of 11, 7.6, and 5.8 uM, respectively. |
| PC-73084 |
Autogramin-1
Autophagy inhibitor
|
Autogramin-1 is a potent autophagy inhibitor, inhibits autophagy induced by either starvation or mTORC1 inhibition with IC50 of 0.17 and 0.44 uM, respectively. |
| PC-73072 |
LCC03
Autophagy inducer
|
LCC03 is a salicylanilide derivative and autophagy inducer, dose-dependently suppresses proliferation and retarded cell-cycle progression in CRPC cells (IC50, 0.69 to 4.8 uM). |
| PC-73004 |
Autophagy inhibitor EACC
Autophagy inhibitor
|
Autophagy inhibitor EACC (EACC) is a novel small molecule, reversible inhibitor of autophagy, inhibits autophagic flux by blocking autophagosomelysosome fusion. |
| PC-72988 |
Autophagy activator EN6
Autophagy activator
|
Autophagy activator EN6 (EN6) is a small-molecule in vivo activator of autophagy, covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase (vacuolar H+-ATPase). |
| PC-72715 |
Autophazole
Autophagy inhibitor
|
Autophazole is a novel autophagy inhibitor, promotes cancer cell death via caspase activation. |
| PC-72653 |
DC-LC3in-D5
LC3 Protein modulator
|
DC-LC3in-D5 is a small molecule covalent modulator of LC3A/B and autophagy inhibitor, binds to LC3B and covalently modifies Lysine 49. |
| PC-72577 |
CBK288679
Autophagy inhibitor
|
CBK288679 (CBK79) is a novel compound that impairs both protein degradation by the ubiquitin-proteasome system (UPS) and autophagy. |
| PC-38229 |
Autoquin
Autophagy inhibitor
|
Autoquin is a novel autophagy inhibitor (IC50=0.56 uM) by indirect modulation of the activity of the lysosomal enzymes acid sphingomyelinase and acid ceramidase. |
| PC-36107 |
SLLN-15
Autophagy inducer
|
SLLN-15 (Autophagy inducer SLLN-15) is a potent, orally available inducer of autophagy that selectively activated cytostatic macroautophagy/autophagy in TNBC preclinical models, promotes AURKA degradation. |
| PC-35838 |
DC661
Autophagy inhibitor, PPT1 inhibitor
|
DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1). |
