Cat. No. |
Product Name |
Information |
PC-61297 |
XRK3F2
p62 inhibitor
|
XRK3F2 is a specific ZZ-domain of ubiquitin-binding protein p62 (Sequestosome 1) inhibitor that inhibits MM cell growth and BMSC growth enhancement of human MM cells. |
PC-60602 |
Lucanthone
APE1 inhibitor
|
Lucanthone is an ionizing radiation enhancer and apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor with IC50 of 5 uM for inhibition of APE1 incision of depurinated plasmid DNA, also may act as an inhibitor of protein palmitoyl thioesterase 1 (PPT1). |
PC-60601 |
Lys05
Kir4.1 inhibitor
|
Lys05 (Lys01 trihydrochloride, PS-1001) is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), also is a Kir4.1 inhibitor. |
PC-60599 |
ROC-325
|
ROC-325 (ROC 325, ROC325) is a novel, orally available inhibitor of lysosomal-mediated autophagy. |
PC-42080 |
SMER-28
VCP/p97 activator
|
SMER28 is a small-molecule enhancer/inducer of Autophagy, SMER28 is a small molecule activator of VCP/p97. |
PC-42248 |
STF-62247
|
STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells. |
PC-43929 |
GSK4112
Rev-erbα agonist
|
GSK4112 (SR6452) is a potent and selective small molecule Rev-erbα agonist with EC50 of 0.4 uM in biochemical assays. |
PC-21907 |
Hycanthone
APE1 inhibitor
|
Hycanthone is a thioxanthenone DNA intercalator, inhibits RNA synthesis as well as the DNA topoisomerases I and II, inhibits apurinic endonuclease 1 (APE1) incision of depurinated plasmid DNA with IC50 of 80 nM. |
PC-21540 |
RH1115
Autophagy activator
|
RH1115 is a small molecule activator and inducer of autophagy targeting Lamin A/C and LAMP1, induces changes to LAMP1 vesicle properties and alters lysosome positioning. |
PC-20502 |
JS-017
A2E degrader
|
JS-017 (JS017) is a small molecule degrader of N-retinylidene-N-retinylethanolamine (A2E), one of the components of lipofuscin, degrades A2E-BDP from ARPE-19 cells with IC50 of 3.239 uM. |
PC-38562 |
Autophagy inducer D61
Autophagy inducer
|
Autophagy inducer D61 is a small molecule autophagy inducer with antibacterial activity, induces LC3II and promotes aggregation of LC3II near Salmonella. |
PC-36107 |
SLLN-15
|
SLLN-15 (Autophagy inducer SLLN-15) is a potent, orally available inducer of autophagy that selectively activated cytostatic macroautophagy/autophagy in TNBC preclinical models, promotes AURKA degradation and . |