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Cat. No. Product Name Information
PC-61297

XRK3F2

p62 inhibitor

XRK3F2 is a specific ZZ-domain of ubiquitin-binding protein p62 (Sequestosome 1) inhibitor that inhibits MM cell growth and BMSC growth enhancement of human MM cells.
PC-60602

Lucanthone

APE1 inhibitor

Lucanthone is an ionizing radiation enhancer and apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor with IC50 of 5 uM for inhibition of APE1 incision of depurinated plasmid DNA, also may act as an inhibitor of protein palmitoyl thioesterase 1 (PPT1).
PC-60601

Lys05

Kir4.1 inhibitor

Lys05 (Lys01 trihydrochloride, PS-1001) is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), also is a Kir4.1 inhibitor.
PC-60599

ROC-325

ROC-325 (ROC 325, ROC325) is a novel, orally available inhibitor of lysosomal-mediated autophagy.
PC-42080

SMER-28

VCP/p97 activator

SMER28 is a small-molecule enhancer/inducer of Autophagy, SMER28 is a small molecule activator of VCP/p97.
PC-42248

STF-62247

STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.
PC-43929

GSK4112

Rev-erbα agonist

GSK4112 (SR6452) is a potent and selective small molecule Rev-erbα agonist with EC50 of 0.4 uM in biochemical assays.
PC-21907

Hycanthone

APE1 inhibitor

Hycanthone is a thioxanthenone DNA intercalator, inhibits RNA synthesis as well as the DNA topoisomerases I and II, inhibits apurinic endonuclease 1 (APE1) incision of depurinated plasmid DNA with IC50 of 80 nM.
PC-21540

RH1115

Autophagy activator

RH1115 is a small molecule activator and inducer of autophagy targeting Lamin A/C and LAMP1, induces changes to LAMP1 vesicle properties and alters lysosome positioning.
PC-20502

JS-017

A2E degrader

JS-017 (JS017) is a small molecule degrader of N-retinylidene-N-retinylethanolamine (A2E), one of the components of lipofuscin, degrades A2E-BDP from ARPE-19 cells with IC50 of 3.239 uM.
PC-38562

Autophagy inducer D61

Autophagy inducer

Autophagy inducer D61 is a small molecule autophagy inducer with antibacterial activity, induces LC3II and promotes aggregation of LC3II near Salmonella.
PC-36107

SLLN-15

SLLN-15 (Autophagy inducer SLLN-15) is a potent, orally available inducer of autophagy that selectively activated cytostatic macroautophagy/autophagy in TNBC preclinical models, promotes AURKA degradation and .

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