| Cat. No. |
Product Name |
Information |
| PC-63057 |
Elaiophylin
Autophagy inhibitor
|
Elaiophylin (Gopalamicin; Salbomycin; Azalomycin B) is a macrodiolide antibiotic that shows in vitro anti-protozoal activity against both Plasmodium and Trypanosoma (IC50=370 and 460 ng/ml, respectively) and cytotoxicity against human fetal lung fibroblast MRC-5 cells (IC50=870 ng/ml). |
| PC-61671 |
ZPCK
Autophagy inhibitor
|
ZPCK (NSC 251810, SL 01) is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells. |
| PC-61297 |
XRK3F2
p62 inhibitor
|
XRK3F2 is a specific ZZ-domain of ubiquitin-binding protein p62 (Sequestosome 1) inhibitor that inhibits MM cell growth and BMSC growth enhancement of human MM cells. |
| PC-70317 |
BRD5631
Autophagy inducer
|
BRD5631 is a small-molecule enhancer of autophagy through an mTOR-independent pathway. |
| PC-60601 |
Lys05
Autophagy inhibitor, Kir4.1 inhibitor
|
Lys05 (Lys01 trihydrochloride, PS-1001) is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), also is a Kir4.1 inhibitor. |
| PC-60600 |
Lys01
Autophagy inhibitor
|
Lys01 is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), inhibits cell viability of 1205Lu, c8161, LN229, HT-29 cells with IC50s of 3.6, 3.8, 7.9, 6.0 uM respectively. |
| PC-60599 |
ROC-325
Autophagy inhibitor
|
ROC-325 (ROC 325, ROC325) is a novel, orally available inhibitor of lysosomal-mediated autophagy. |
| PC-60596 |
Hydroxychloroquine sulfate
Autophagy inhibitor, TLR7/9 inhibitor
|
Hydroxychloroquine sulfate is a synthetic antimalarial drug that inhibits autophagy, also inhibits TLR7 and TLR9 signaling, also inhibits peptidyl arginine deiminase 4 (PAD4). |
| PC-60217 |
AUTEN-67
MTMR14 inhibitor, Autophagy inducer
|
AUTEN-67 is a small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14. |
| PC-70067 |
AUTEN-99
MTMR14 inhibitor, autophagy inducer
|
AUTEN-99 is a small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-70066 |
AUTEN-99 hydrobromide
MTMR14 inhibitor, autophagy inducer
|
A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-45633 |
Hemin
CLEC-2 agonist, HO-1 inducer
|
Hemin is an iron-containing porphyrin as heme oxygenase (HO)-1 inducer, also is a CLEC-2 agonist that induces CLEC-2-mediated platelet aggregation. |
