| Cat. No. |
Product Name |
Information |
| PC-Ab1061 |
Urabrelimab
|
SRF-231 is fully human mAb for CD47, binds with high affinity to CD47, stimulates phagocytosis and the killing of cancer cells in vitro and has potent anti-tumor activity preclinically, both as monotherapy and in combination settings.disrupts the CD47/SIRPα interaction without causing hemagglutination or RBC phagocytosis. SRF231 exerts antitumor activity in vitro through both phagocytosis and cell death in a manner dependent on the activating Fc-gamma receptor (FcγR), CD32a. In tumor-bearing mic |
| PC-49138 |
Denecimig
Anti-Factor IX
|
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against F9 (coagulation factor
9, coagulation factor IX). Isotype: IgG4-kappa. Anti-[F9 (coagulation factor 9, coagulation factor IX) activated form and F10 (coagulation factor 10, coagulation factor X)], human monoclonal antibody, bispecific, bivalent. |
| PC-49137 |
Delpacibart
Anti-TFRC
|
Delpacibart is a humanized mnonoclonal antibody against TFRC transferrin receptor (TfR1). Isotype: IgG1-kappa. Anti-[human TFRC (transferrin receptor, TfR1)], humanized monoclonal antibody. |
| PC-49136 |
Dargistotug
Anti-TIGIT
|
Dargistotug is a humanized mnonoclonal antibody against TIGIT (VSIG9). Isotype: IgG1-kappa. Anti-[human TIGIT (T-cell immunoreceptor with Ig domain and ITIM, V-set Ig member 9, VSIG9, V-set and transmembrane member 3, VSTM3)], human monoclonal antibody. |
| PC-49135 |
Danvilostomig
Anti-CTLA4/PD-1
|
IgG1-kappa_scFv, anti-[human CTLA4 (cytotoxic T-lymphocyte-associated antigen 4, cytotoxic Tlymphocyte-associated protein 4, CTLA-4, CD152)], each heavy chain being fused to a scFv anti-human PDCD1 (programmed cell death 1, PD1, PD-1, CD279)], human and humanized monoclonal antibody, tetravalent, bispecific. |
| PC-49134 |
Danburstotug
Anti-PD-L1
|
Danburstotug (IMC 001, STI A1015, STI 3031) is a fully human monoclonal antibody against CD274 (PD-L1). Isotype: IgG1-lambda. Anti-[human CD274 (programmed cell death 1 ligand 1, PDL1, PDL1, B7 homologue 1, B7H1)], human monoclonal antibody. |
| PC-49133 |
Dalnicastobart
Anti-CD40 (TNFRSF5)
|
Dalnicastobart is a humanized mnonoclonal antibody against CD40 (TNFRSF5). Isotype: IgG1-kappa, Anti-[human CD40 (tumor necrosis factor receptor superfamily member 5, TNFRSF5, p50)], human monoclonal antibody. |
| PC-49129 |
Calpurbatug
Anti-HU/IHF
|
Calpurbatug is a humanized mnonoclonal antibody against bacteria proteins HU (histone-like protein, nucleoid-associated protein, HLP) and IHF (integration host factor). Isotype: IgG1-kappa, Anti-[bacteria proteins HU (histone-like protein, nucleoid-associated protein, HLP) and IHF (integration host factor) conserved epitopes], human mnonoclonal antibody. |
| PC-49125 |
Bremzalerbart
Anti-Bet V1
|
Bremzalerbart is a monoclonal antibody directed against Bet v 1 allergen (Betula alleghaniensis (yellow birch) pollen allergen 1). Isotype: IgG4-kappa, Anti-[Bet v 1 (Betula alleghaniensis (yellow birch) pollen allergen 1], human monoclonal antibody. |
| PC-49124 |
Boserolimab
Anti-CD27 (TNFRSF7)
|
Boserolimab (MK-5890) is a humanized agonist monoclonal antibody that binds to CD27 to provide a costimulatory signal that enhances T-cell-mediated responses, shows potential immunostimulatory and antineoplastic activities. |
| PC-49123 |
Bempikibart
Anti-IL7R (CD127)
|
Bempikibart is a fully human immunoglobulin G1-kappa against IL7R (CD127), Isotype: IgG1-kappa, Anti-[human IL7R (interleukin 7 receptor, IL7RA, CD127)], human monoclonal antibody. |
| PC-49122 |
Belrestotug
Anti-TIGIT
|
Belrestotug (EOS-448, EOS 884448, GSK 4428859, GSK 4428859A) is a fully human IgG1 TIGIT antagonist monoclonal antibody, fully prevents CD155-mediated inhibition. |
