| Cat. No. |
Product Name |
Information |
| PC-20177 |
JNJ-1802
DENV inhibitor
|
JNJ-1802 (Mosnodenvir) is a highly potent, pan-serotype dengue virus (DENV) inhibitor (EC50=0.04 nM-1.8 nM), blocks the NS3-NS4B interaction within the viral replication complex (EC50=1.4 nM, DENV-2). |
| PC-49197 |
U18666A
NPC1 inhibitor
|
U18666A is a cationic sterol that blocks the movement of cholesterol out of lysosomes and also inhibits Ebola virus infections, targets niemann-Pick C1 (NPC1) which exports cholesterol derived from receptor-mediated uptake of LDL, and mediates cellular entry of Ebola virus. |
| PC-47063 |
RK-0404678
DENV2 RdRp inhibitor
|
RK-0404678 is a potent, small molecule inhibitor of DENV type 2 (DENV2) RdRp activities, exhibits in cellulo antiviral EC50 of 6.0 uM for DENV2. |
| PC-38666 |
NITD008
Flavivirus inhibitor
|
NITD008 is a selective, adenosine-based flavivirus inhibitor, inhibits dengue virus (DENV, EC50= 0.64 μM), HCV and cellular entry of ZIKV, also has potent antiviral activity against EV71 with EC50 of 0.67 uM in cell culture. |
| PC-38559 |
Filovirus inhibitor compd-A
Filovirus entry inhibitor
|
Filovirus inhibitor compd-A is a small molecule filovirus entry inhibitor targeting the endosomal receptor NPC1 binding site, shows potent inhibitory activity against both Ebola and Marburg viruses with IC50 of 0.86 uM against pseudotyped Marburg virus entry. |
| PC-38463 |
ASN03576800
EBOV Vp40 inhibitor
|
ASN03576800 is a potent, small molecule inhibitor of matrix protein vp40 of ebola virus (EBOV), occupied the RNA binding region of VP40 with a Glide score of -7.66 and the Glide energy is -31.88 Kcal/mol. |
| PC-72500 |
JNJ-A07
DENV inhibitor
|
JNJ-A07 is a highly potent, highly specific dengue virus (DENV) inhibitor targeting the NS3-NS4B interaction. |
| PC-35947 |
JBJ-01-162-04
DENV inhibitor
|
JBJ-01-162-04 is a small molecule targeting the flavivirus E protein with broad-spectrum activity, shows activity against DENV in the infectivity assay with IC90 of 0.1 uM. |
| PC-35651 |
ZIKV inhibitor K22
|
ZIKV inhibitor K22 is a small molecule that exerts a potent antiviral activity against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibits ZIKV with IC50 of 2.1 uM (48 h p.i). |
| PC-35010 |
IHVR-19029
ER α-glucosidase inhibitor
|
IHVR-19029 is a novel antiviral compound that acts as ER α-glucosidase inhibitor, synergistically inhibits the replication of Yellow fever and Ebola viruses in cultured cells combined with favipiravir (T-705). |
| PC-35008 |
ST-148
DENV inhibitor
|
ST-148 is a potent, broad-spetrum inhibitor of dengue virus (DENV) replication, inhibits DENV-2 wth EC50 of 16 nM in viral titer reduction assays, interacts with the DENV capsid protein. |
| PC-35007 |
VGTI-A3-03
DENV inhibitor
|
VGTI-A3-03 is a potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM), directly binds DENV capsid protein. |
