| Cat. No. |
Product Name |
Information |
| PC-60236 |
LY2922470
GPR40 agonist
|
LY2922470 (LY-2922470) is a potent, selective, orally available GPR40 agonist with EC50 of 7 nM. |
| PC-60235 |
LY3104607
GPR40 agonist
|
LY3104607 (LY-3104607) is a potent, selective, orally available GPR40 agonist with Ki of 15 nM, β-arrestin EC50 of 108 nM. |
| PC-60167 |
GPR120 agonist 4x
GPR120 (FFAR4) agonist
|
GPR120 agonist 4x is a potent, selective, orally bioavailable GPR120 agonist with EC50 of 42 nM in calcium flux assays. |
| PC-70042 |
DC-260126
GPR40 agonist
|
DC-260126 is a potent GPR40 agonist with IC50 of 6.28 uM for inhibition of Ca2+ stimulated by linoleic acid. |
| PC-42610 |
TAK-875
GPR40 agonist
|
TAK-875 (Fasiglifam) is a potent, selective, orally bioavailable GPR40 (FFA1) agonist with EC50 of 14 nM. |
| PC-42283 |
TUG-891
GPR120 (FFAR4) agonist
|
TUG-891 is a potent, selective human GPR120 (FFA4) agonist with pEC50 of 7.22. |
| PC-45843 |
GW-1100
GPR40 inhibitor
|
GW-1100 (SB-376752) is a potent, selective GPR40 antagonist that dose dependently inhibits GPR40-mediated Ca2+ elevations stimulated by GW9508 and linoleic acid with pIC50 of 5.99. |
| PC-45779 |
GSK137647A
GPR120 (FFAR4) agonist
|
GSK-137647 (GSK-137647A) is a potent, selective GPR120 (FFA4) agonist with pEC50 of 6.3, >100-fold selectivity over the FFA1, FFA2, and FFA3 receptors. |
| PC-42400 |
GPR120 agonist 1
GPR120 (FFAR4) agonist
|
GPR120 agonist 1 is a potent, fully selective, orally available GPR120 (FFA4) agonist with pEC50 of 7.62. |
| PC-43813 |
AMG 837
GPR40 agonist
|
AMG 837 is a potent partial GPR40 (FFA1) agonist (EC50=13 nM for hGPR40). |
| PC-20870 |
GPR40 agonist AP8
GPR40 agonist
|
GPR40 agonist AP8 is a potent, selective, full allosteric agonist (AgoPAM) of GPR40 with EC50 of 0.6 nM, Emax=268%. |
| PC-20869 |
GPR40 agonist AP4
GPR40 agonist
|
GPR40 agonist AP4 is a potent, selective, full allosteric agonist (AgoPAM) of GPR40 with EC50 of 0.08 nM, Emax=283%. |
