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Cat. No. Product Name Information
PC-49277

(R)-AS-1

EAAT2 PAM

 (R)-AS-1 is an orally bioavailable, selective positive allosteric modulator (PAM) of the glutamate transporter EAAT2 with EC50 of 11 nM and Emax of 251%, shows potent antiseizure activity in vivo.
PC-72279

MC-100093

GLT-1 modulator

 MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.
PC-35512

WAY-213613

WAY-213613 (WAY213613) is a potent, non-substrate inhibitor of EAAT2 (GLT-1) with IC50 of 85 nM, displays > 44-fold selectivity over EAAT1 and EAAT3.
PC-35511

NBI-59159

NBI-59159 (NBI59159) is a potent EAAT3-preferring inhibitor..
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