| Cat. No. |
Product Name |
Information |
| PC-61458 |
PF0346275
|
A potent, selective, orally available GlyT1 inhibitor with Ki of 11.6 nM, without activity against GlyT2 (IC50>10 uM). |
| PC-61457 |
DCCCyB
|
A potent, selective, orally available GlyT1 inhibitor with IC50 of 29 nM, demonstrates excellent in vivo occupancy of GlyT1 transporters in vivo.. |
| PC-61002 |
ASP2535
|
A potent, selective, brain permeable, orally available glycine transporter-1 (GlyT1) inhibitor with IC50 of 92 nM (rat GlyT1), 50-fold selectivity over GlyT2. |
| PC-60977 |
AMG 747
|
A nanomolar potent, selective, and orally bioavailable glycine transporter type-1 (GlyT1) inhibitor for the treatment of negative symptoms associated with schizophrenia. |
| PC-60444 |
Org 25935
|
A potent, selective glycine transporter 1 (GlyT1) inhibitor with IC50 of 100 nM. |
| PC-42145 |
LY-2365109 hydrochloride
|
A potent and selective GlyT1 inhibitor with IC50 of 15.8 nM, displays no activity for GlyT2 (IC50>30 uM). |
| PC-42707 |
Bitopertin R enantiomer
|
A potent and selective GlyT1 inhibitor with EC50 of 54 nM. |
