| Cat. No. |
Product Name |
Information |
| PC-42456 |
Retaspimycin hydrochloride
HSP90 inhibitor
|
A water-soluble derivative of 17-AAG and HSP90 inhibitor. |
| PC-42156 |
HA-15
GRP78 inhibitor
|
HA-15 is a specifc inhibitor of the chaperone BiP (Binding immunoglobulin protein, GRP78 or HSPA5) that displays anti-cancerous activity on melanoma cells, including BRAF resistance melanoma cells. |
| PC-42278 |
KRIBB11
HSF1 inhibitor
|
KRIBB11 is a small molecule heat shock factor 1 (HSF1) inhibitor with IC50 of 1.2 uM. |
| PC-42459 |
BIIB021
HSP90 inhibitor
|
BIIB021 is a potent, selective, orally available HSP90 inhibitor with Ki of 1.7 nM for Hsp90α. |
| PC-42558 |
Alvespimycin
HSP90 inhibitor
|
Alvespimycin (17-DMAG) is a potent, orally bioavailable Hsp90 inhibitor with binding EC50 of 62 nM. |
| PC-42457 |
17-AAG
HSP90 inhibitor
|
17-AAG (Tanespimycin) is a potent Hsp90 inhibitor with IC50 of 5 nM in cell-free assays. |
| PC-42747 |
VER-155008
Hsp70 inhibitor
|
VER-155008 is a potent Hsp70 family (Hsc70/Hsp7/Grp78) inhibitor with Kd of 80 nM for Grp78. |
| PC-42748 |
NVP-BEP800
Hsp90β inhibitor
|
NVP-BEP800 (VER-82576) is a potent and selective Hsp90β inhibitor with IC50 of 58 nM. |
| PC-42461 |
NVP-AUY922
HSP90 inhibitor
|
NVP-AUY922 (Luminespib, AUY922) is a potent and selective HSP90 inhibitor with IC50 of 21 and 7.8 nM for HSP90β and HSP90α, respectively. |
| PC-45521 |
PU-WS13
Grp94 inhibitor
|
PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM. |
| PC-21759 |
HYOU1 inhibitor 52
HYOU1 inhibitor
|
HYOU1 inhibitor 52 is a first-in-class inhibitor for Hypoxia up-regulated protein 1 (HYOU1, GRP170/ORP150), decreases significantly the levels of the cytokine Interleukin 6 (IL-6) in LPS (10 ng/mL)-treated WT-MΦs with IC50 of 0.57 uM. |
| PC-21758 |
HYOU1 inhibitor 33
HYOU1 inhibitor
|
HYOU1 inhibitor 33 is a first-in-class inhibitor for Hypoxia up-regulated protein 1 (HYOU1, GRP170/ORP150), decreases significantly the levels of the cytokine Interleukin 6 (IL-6) in LPS (10 ng/mL)-treated WT-MΦs with IC50 of 2.57 uM. |
