Cat. No. |
Product Name |
Information |
PC-61032 |
4-Br-BnIm
Grp94 inhibitor
|
4-Br-BnIm is a potent, subtype-selective Grp94 inhibitor with Kd of 0.96 uM, 13-fold selectivity over Hsp90α. |
PC-60683 |
SNX-0723
HSP90 inhibitor
|
SNX-0723 is a selective, brain-permeable, orally acitve small-molecule inhibitor of Hsp90 (IC50=14 nM) that inhibits alpha-synuclein oligomerization with EC50 of 48 nM. |
PC-60660 |
KU-32
HSP90 inhibitor, Hsp70 inducer
|
KU-32 is a novel, novobiocin-based, C-terminal inhibitor of Hsp90 and a potent inducer of Hsp70. |
PC-60609 |
KU675
HSP90 inhibitor
|
KU675 is a second-generation C-terminal Hsp90 inhibitor with Kd of 191 and 726 uM for Hsp90α and Hsp90β, respectively. |
PC-60545 |
Arimoclomol maleate
|
Arimoclomol maleate (BRX-220) is a nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
PC-60544 |
Arimoclomol
|
Arimoclomol (BRX-220) is a nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
PC-60497 |
SM253
HSP90 inhibitor
|
SM253 (SM 253, SM-253) is a novel potent Hsp90 inhibitor that does not induce heat shock response. |
PC-60471 |
MPC-3100
HSP90 inhibitor
|
MPC-3100 is a novel potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM. |
PC-60470 |
MPC-0767
HSP90 inhibitor
|
MPC-0767 (MPC0767, MPC3100 mesylate hydrate) is an L-alanine ester prodrug of MPC-3100, which is a potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM. |
PC-60233 |
CCT251236
Pirin ligand
|
CCT251236 (CCT-251236) is a potent, orally available Pirin ligand (Ki=28 nM), blocks the HSF1-mediated induction of both HSP72 and HSP27. |
PC-60157 |
PU-H54
|
PU-H54 is a potent, selective Grp94 inhibitor. |
PC-42460 |
PF-04929113 Mesylate
HSP90 inhibitor
|
The prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor. |