| Cat. No. |
Product Name |
Information |
| PC-42380 |
VUF10460
Histamine H4 agonist
|
VUF10460 is a potent, selective histamine H4 receptor agonist with pKi of 7.46 and 8.22 for rat and human H4, respectively. |
| PC-45369 |
Decloxizine
Histamin H1 antagonist
|
Decloxizine (UCB-1402, NSC-289116) is a potent histamine 1 (H1) receptor antagonist. |
| PC-42908 |
ABT-239
Histamine H3 antagonist
|
ABT-239 is a potent and selective Histamine H3 receptor antagonist with Ki of 0.1-5.8 nM (human, rat H3). |
| PC-42911 |
Pitolisant hydrochloride
H3 receptor antagonist
|
Pitolisant hydrochloride (Ciproxidine, BF2649) is a potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM. |
| PC-42909 |
Pitolisant
H3 receptor antagonist
|
Pitolisant (Tiprolisant, BF-2649, BF 2.649) is a potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM. |
| PC-45163 |
Alcaftadine
Histamine H1 antagonist
|
Alcaftadine (R-89674) is a H1 histamine receptor antagonist that used for prevention of allergic conjunctivitis, has a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. |
| PC-45251 |
Tripelennamine hydrochloride
H1 receptor antagonist
|
Tripelennamine hydrochloride (Pyribenzamine hydrochloride) is the first-generation antihistamine that acts primarily as H1 receptor antagonist. |
| PC-24426 |
Contilisant
H3R/MAO/AChE inhibitor, S1R agonist
|
Contilisant is a permeable, antioxidant, and neuroprotectant agent, shows high nM affinity at H3R (Ki=10.8 nM, hH3R) and excellent inhibition of the monoamine oxidases and cholinesterases (hAChE IC50=0.53 uM), is a selective S1R agonist (Ki=65.2 nM). |
| PC-24402 |
Promethazine hydrochloride
Histamine antagonist
|
Promethazine hydrochloride is an orally active histamine receptor antagonist, shows antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. |
| PC-23593 |
ADS1017 trihydrochloride
H3R antagonist
|
ADS1017 trihydrochloride is a potent, selective histamine H3 receptor antagonist with pKi of 7.9/6.8 for rH3R/hH3R in radioligand binding assays respectively, 20-fold selective over H4R. |
| PC-23592 |
ADS1017
H3R antagonist
|
ADS1017 is a potent, selective histamine H3 receptor antagonist with pKi of 7.9/6.8 for rH3R/hH3R in radioligand binding assays respectively, 20-fold selective over H4R. |
| PC-23507 |
Latrepirdine dihydrochloride
97657-92-6
|
Latrepirdine dihydrochloride (Dimebolin, Dimebone) is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors, stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion. |
