Cat. No. |
Product Name |
Information |
PC-49046 |
ND-2110
IRAK4 inhibitor
|
ND2110 is a highly selective and bioavailable small molecule IRAK4 inhibitor with IC50 of 7.5 nM, no significant activity against IRAK1 (IC50>2000 nM). |
PC-38157 |
ND2158
IRAK4 inhibitor
|
ND2158 (ND-2158) is a highly potent and selective IRAK4 inhibitor with IC50 of 1.3 nM. |
PC-38076 |
THZ-2-118
IRAK1 inhibitor
|
THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM. |
PC-38073 |
JH-X-119-01
IRAK1 inhibitor
|
JH-X-119-01 is a highly potent, selective and covalent inhibitor of IRAK1 with IC50 of 9 nM. |
PC-35553 |
PF-06426779
|
PF-06426779 (PF06426779) is a potent, selective IRAK4 inhibitor with IC50 of 1 nM against full-length IRAK4 kinase and cell-based IC50 of 12 nM. |
PC-50002 |
CA-4948
IRAK4 inhibitor
|
Emavusertib (CA-4948) is a potent, selective and orally active IRAK4 inhibitor with IC50 of 31.7 nM. |
PC-45740 |
PF-06650833
|
PF-06650833 (PF06650833) is a potent and selective IRAK4 inhibitor with IC50 of 0.2 nM. |
PC-21921 |
BIO-7488
IRAK4 inhibitor
|
BIO-7488 (BIO7488) is the first potent, selective, and CNS-penetrant IRAK4 inhibitor with IC50 of 0.5 nM (1 mM ATP). |
PC-21202 |
KME-3859
IRAK4 inhibitor
|
KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1. |
PC-21201 |
KME-2780
IRAK1/4 inhibitor
|
KME-2780 (KME2780) is a potent and selective dual IRAK1 and IRAK4 (IRAK1/4) inhibitor with IC50 of 19 and 0.5 nM, respectively. |
PC-49845 |
GLPG2534
IRAK4 inhibitor
|
GLPG2534 (GLPG 2534) is a potent, selective IRAK4 inhibitor with therapeutic potential in chronic inflammatory skin diseases. |
PC-38684 |
BAY1830839
IRAK4 inhibitor
|
BAY1830839 is a potent, selective IRAK4 inhibitor with IC50 of 3.0 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway. |