You are here:Home-Chemical Inhibitors & Agonists-Immunology/Inflammation-IRAK

Request The Product List ofIRAK IRAK

Cat. No. Product Name Information
PC-49046

ND-2110

IRAK4 inhibitor

ND2110 is a highly selective and bioavailable small molecule IRAK4 inhibitor with IC50 of 7.5 nM, no significant activity against IRAK1 (IC50>2000 nM).
PC-38157

ND2158

IRAK4 inhibitor

ND2158 (ND-2158) is a highly potent and selective IRAK4 inhibitor with IC50 of 1.3 nM.
PC-38076

THZ-2-118

IRAK1 inhibitor

THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM.
PC-38073

JH-X-119-01

IRAK1 inhibitor

JH-X-119-01 is a highly potent, selective and covalent inhibitor of IRAK1 with IC50 of 9 nM.
PC-35553

PF-06426779

PF-06426779 (PF06426779) is a potent, selective IRAK4 inhibitor with IC50 of 1 nM against full-length IRAK4 kinase and cell-based IC50 of 12 nM.
PC-50002

CA-4948

IRAK4 inhibitor

Emavusertib (CA-4948) is a potent, selective and orally active IRAK4 inhibitor with IC50 of 31.7 nM.
PC-45740

PF-06650833

PF-06650833 (PF06650833) is a potent and selective IRAK4 inhibitor with IC50 of 0.2 nM.
PC-21921

BIO-7488

IRAK4 inhibitor

BIO-7488 (BIO7488) is the first potent, selective, and CNS-penetrant IRAK4 inhibitor with IC50 of 0.5 nM (1 mM ATP).
PC-21202

KME-3859

IRAK4 inhibitor

KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1.
PC-21201

KME-2780

IRAK1/4 inhibitor

KME-2780 (KME2780) is a potent and selective dual IRAK1 and IRAK4 (IRAK1/4) inhibitor with IC50 of 19 and 0.5 nM, respectively.
PC-49845

GLPG2534

IRAK4 inhibitor

GLPG2534 (GLPG 2534) is a potent, selective IRAK4 inhibitor with therapeutic potential in chronic inflammatory skin diseases.
PC-38684

BAY1830839

IRAK4 inhibitor

BAY1830839 is a potent, selective IRAK4 inhibitor with IC50 of 3.0 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com