| Cat. No. |
Product Name |
Information |
| PC-61694 |
PF-06260933 dihydrochloride
MAP4K4 inhibitor
|
PF-06260933 dihydrochloride is a potent, selective and orally bioavailable MAP4K4 inhibitor with kinase IC50 of 3.7 nM, cell IC50 of 160 nM. |
| PC-61165 |
MAP4K4-IN-11e
MAP4K4 inhibitor
|
MAP4K4-IN-11e is a potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases. |
| PC-60014 |
PF-06260933
MAP4K4 inhibitor
|
PF-06260933 (PF06260933, PF6260933) is a potent, selective, orally available MAP4K4 inhibitor with IC50 of 3.7 nM. |
| PC-42105 |
GNE-495
MAP4K4 inhibitor
|
GNE-495 (GNE495) is a potent and highly selective, cell permeable MAP4K4 inhibitor with IC50 of 3.7 nM. |
| PC-28613 |
GNE-220 hydrochloride
MAP4K4 inhibitor
|
GNE-220 hydrochloride is a potent and selective inhibitor of MAP4K4 with IC50 of 7 nM, also inhibits MINK (MAP4K6), DMPK and KHS1 (MAP4K5) with IC50 of 9 nM, 476 nM and 1,110 nM. |
| PC-28611 |
F389-0736
MAP4K inhibitor
|
F389-0736 is a potent, selective and effective MAP4K4 inhibitor with IC50 of 44 nM. |
| PC-26554 |
MAP4K4 inhibitor 15f
MAP4K4 inhibitor
|
MAP4K4 inhibitor 15f is a potent, selective inhibitor of MAP4K4 with IC50 of 89 nM, shows neuroprotective effects. |
| PC-22569 |
HPK1-IN-3
HPK1 inhibitor
|
HPK1-IN-3 is a potent, selective, ATP-competitive hematopoietic progenitor kinase 1 (HPK1, MAP4K1) inhibitor with IC50 of 0.25 nM in TR-FRET assays. |
| PC-22568 |
KHK-6
HPK1 inhibitor
|
KHK-6 is a potent, selective, ATP-competitive inhibitor of serine/threonine kinase hematopoietic progenitor kinase 1 (HPK1, MAP4K1) with IC50 of 20 nM. |
