| Cat. No. |
Product Name |
Information |
| PC-60053 |
Solriamfetol hydrochloride
|
Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
| PC-45481 |
Diclofensine
Monoamine reuptake inhibitor
|
Diclofensine (Ro 8-4650) is an antidepressant that acts as a triple monoamine reuptake inhibitor. |
| PC-45480 |
Diclofensine hydrochloride
Monoamine reuptake inhibitor
|
Diclofensine (Ro 8-4650) hydrochloride is an antidepressant that acts as a triple monoamine reuptake inhibitor. |
| PC-46649 |
Paroxetine hydrochloride
GRK2 inhibitor, SSRI
|
Paroxetine hydrochloride is an oral, selective serotonin reuptake inhibitor (SSRI), also is a direct, selective inhibitor of G protein-coupled receptor kinase 2 (GRK2) with pIC50 of 5.6. |
| PC-45454 |
Amitifadine hydrochloride
Monoamine reuptake inhibitor
|
Amitifadine hydrochloride (DOV-21947 hydrochloride) is a triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
| PC-45076 |
Valbenazine
VMAT2 inhibitor
|
Valbenazine (NBI-98854) is a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor with Ki of 110-190 nM. |
| PC-27193 |
B0AT1 inhibitor compound 3
B0AT1 inhibitor
|
B0AT1 inhibitor compound 3 is a potent, selective, allosteric inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 513 nM and 295 nM for human and mouse B0AT1 respectively. |
| PC-27192 |
JX225
B0AT1 inhibitor
|
JX225 is a potent, high-affinity inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.07 uM in FLIPR assays, and 0.44 uM in radioactive L-leucine uptake assays. |
| PC-27190 |
Cinromide
B0AT1 inhibitor
|
Cinromide is an anticonvulsant agent and potent, selective neutral amino acid transporter B0AT1 (SLC6A19) inhibitor with IC50 of 0.5 uM. |
| PC-26980 |
Fluvoxamine
Serotonin reuptake inhibitor
|
Fluvoxamine is a selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitor and selective sigma-1 receptor agonist, shows ntidepressant activities. |
| PC-26734 |
Sulfasalazine
SLC7A11/xCT inhibitor
|
Sulfasalazine (NSC 667219) is a disease-modifying antirheumatic drug used to treat arthritis and ankylosing spondylitis, is a SLC7A11/xc(-) cystine/glutamate antiporter (xCT) inhibitor, has anti-leukemic activity against primary AML samples. |
| PC-26223 |
Duloxetine
SNRI
|
Duloxetine (LY248686) is a potent serotonin-norepinephrine reuptake inhibitor (SNRI) with Ki of 4.6 nM, also inhibitsvoltage-dependent K+ channels (Kv channels) with IC50 of 4.95 uM for arterial Kv currents. |
