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Cat. No. Product Name Information
PC-72669

Compound 4210

MyD88 inhibitor

Compound 4210 (MyD88 inhibitor 4210) is a small molecule inhibitor of MyD88, inhibits LPS-induced MyD88-mediated NF-kB-dependent expression of reporter activity with IC50 of 10-30 uM.
PC-35815

T5910047

MyD88 inhibitor

T5910047 (T-5910047) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation.
PC-35814

T6167923

T6167923 (T-6167923) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation.
PC-45910

ST-2825

MyD88 inhibitor

ST-2825 (ST2825) is a synthetic peptido-mimetic compound that inhibits MyD88 dimerization in a TIR-dependent manner.
PC-21179

MyD88 inhibitor 15d

MyD88 inhibitor

MyD88 inhibitor 15d is a potent, small molecule inhibitor of MyD88 homodimerization, dose-dependently inhibits LPS-induced IL-6 and TNF-α in macrophages with IC50 of 2.52 and 0.89 uM, respectively.
PC-21177

MyD88 inhibitor C17

MyD88 inhibitor

MyD88 inhibitor C17 is a highly potent inhibitor of myeloid differentiation primary response protein 88 (MyD88), dose-dependently inhibits LPS-induced IL-6 and TNF-α in J774A.1 macrophages with IC50 of 2.17 and 8.17 uM, respectively.
PC-20347

TJ-M2010-2

MyD88 inhibitor

TJ-M2010-2 is a small molecule inhibitor of MyD88 homodimerization, interacts with MyD88 TIR domain.
PC-38670

TJ-M2010-5

MyD88 inhibitor

TJ-M2010-5 is a small molecule MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway.

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