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894787-30-5 A synthetic peptido-mimetic compound that inhibits MyD88 dimerization in a TIR-dependent manner; interferes with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1beta-mediated activation of NF-kappaB transcriptional activity; inhibits IL-1beta-induced production of IL-6 in treated mice, suppresses B cell proliferation and differentiation into plasma cells in response to CpG-induced activation of TLR9; orally active.

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